The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Pathogenic role of fibrinogen in the neuropathology of multiple sclerosis: a tale of sorrows and fears

M Alruwaili, HM Al-Kuraishy, A Alexiou… - Neurochemical …, 2023 - Springer
Multiple sclerosis (MS) is an autoimmune demyelinating neurodegenerative disease of the
central nervous system (CNS) due to injury of the myelin sheath by immune cells. The …

Quercetin as a JAK–STAT inhibitor: a potential role in solid tumors and neurodegenerative diseases

H Zalpoor, M Nabi-Afjadi, R Forghaniesfidvajani… - Cellular & molecular …, 2022 - Springer
The Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway is
involved in many immunological processes, including cell growth, proliferation …

Phyllanthus emblica: a comprehensive review of its phytochemical composition and pharmacological properties

AT Prananda, A Dalimunthe, U Harahap… - Frontiers in …, 2023 - frontiersin.org
Phyllanthus emblica Linn, a prominent member of the euphorbiaceae family, exhibits
extensive distribution across a multitude of tropical and subtropical nations. Referred to as …

De Novo Production of Plant 4′-Deoxyflavones Baicalein and Oroxylin A from Ethanol in Crabtree-Negative Yeast

Z Qian, J Yu, X Chen, Y Kang, Y Ren, Q Liu… - ACS Synthetic …, 2022 - ACS Publications
Baicalein and oroxylin A are well-known medicinal 4′-deoxyflavones found mainly in the
roots of traditional medicinal plant Scutellaria baicalensis Georgi. However, extraction from …

Zebrafish: A model deciphering the impact of flavonoids on neurodegenerative disorders

K Mhalhel, M Sicari, L Pansera, J Chen, M Levanti… - Cells, 2023 - mdpi.com
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …

Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting the intestinal barrier, mitigating oxidative stress …

T Wu, X Wang, H Xiong, Z Deng, X Peng, L Xiao… - Food & Function, 2021 - pubs.rsc.org
Tetrastigma hemsleyanum, a precious edible and medicinal plant in China, has attracted
extensive research attention in recent years due to its high traditional value for the treatment …

A dual function of ferritin (animal and plant): Its holo form for iron supplementation and apo form for delivery systems

X Chang, C Lv, G Zhao - Annual Review of Food Science and …, 2023 - annualreviews.org
Ferritins represent a class of iron storage proteins with detoxification functions. The
importance of these proteins is reflected by their wide distribution throughout the animal and …

Comparative effects of five polymethoxyflavones purified from Citrus tangerina on inflammation and cancer

Q Chen, Y Gu, C Tan, B Sundararajan, Z Li… - Frontiers in …, 2022 - frontiersin.org
Although the Citrus tangerina cultivar “Dahongpao”(CTD) has been established as a rich
source of polymethoxyflavones (PMFs) with anti-inflammatory and anti-cancer properties …

Hypoglycemic flavonoids from Selaginella tamariscina (P. beauv.) spring

HP Long, J Liu, PS Xu, KP Xu, J Li, GS Tan - Phytochemistry, 2022 - Elsevier
Six flavonoids, namely, three undescribed biflavonoids, one undescribed 8-aryl flavonoid,
and two known compounds, were isolated from Selaginella tamariscina (P. Beauv.) Spring …