Machine–learning-enabled metasurface for direction of arrival estimation

M Huang, B Zheng, T Cai, X Li, J Liu, C Qian… - Nanophotonics, 2022 - degruyter.com
Metasurfaces, interacted with artificial intelligence, have now been motivating many
contemporary research studies to revisit established fields, eg, direction of arrival (DOA) …

High‐throughput molecular assays for inclusion in personalised oncology trials–State‐of‐the‐art and beyond

A Edsjö, HG Russnes, J Lehtiö… - Journal of internal …, 2024 - Wiley Online Library
In the last decades, the development of high‐throughput molecular assays has
revolutionised cancer diagnostics, paving the way for the concept of personalised cancer …

Ampullary Adenocarcinoma: A Review of the Mutational Landscape and Implications for Treatment

V Tsagkalidis, RC Langan, BL Ecker - Cancers, 2023 - mdpi.com
Simple Summary Ampullary tumors are rare malignancies of the upper gastrointestinal tract.
Histologic, immunohistochemical and, most recently, genomic biomarkers have been used …

[HTML][HTML] Complete genomic characterization in patients with cancer of unknown primary origin in routine diagnostics

LJ Schipper, KG Samsom, P Snaebjornsson… - ESMO open, 2022 - Elsevier
Background In∼ 3%-5% of patients with metastatic disease, tumor origin remains unknown
despite modern imaging techniques and extensive pathology work-up. With long diagnostic …

Genome-derived classification signature for ampullary adenocarcinoma to improve clinical cancer care

S Chakraborty, BL Ecker, K Seier, VG Aveson… - Clinical Cancer …, 2021 - AACR
Purpose: The clinical behavior of ampullary adenocarcinoma varies widely. Targeted tumor
sequencing may better define biologically distinct subtypes to improve diagnosis and …

A novel approach to quantify heterogeneity of intrahepatic cholangiocarcinoma: the hidden-genome classifier

Y Song, T Boerner, E Drill, P Shin, S Kumar… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: Intrahepatic cholangiocarcinoma (IHC) is a heterogeneous tumor. The hidden-
genome classifier, a supervised machine learning–based algorithm, was used to quantify …

Genome-derived ampullary adenocarcinoma classifier and postresection prognostication

BL Ecker, K Seier, AM Eckhoff, GN Tortorello… - JAMA …, 2024 - jamanetwork.com
Importance Ampullary adenocarcinoma (AA) is characterized by clinical and genomic
heterogeneity. A previously developed genomic classifier defined biologically distinct …

[HTML][HTML] SetQuence & SetOmic: Deep set transformers for whole genome and exome tumour analysis

N Jurenaite, D León-Periñán, V Donath, S Torge… - Biosystems, 2024 - Elsevier
Abstract In oncology, Deep Learning has shown great potential to personalise tasks such as
tumour type classification, based on per-patient omics data-sets. Being high dimensional …

Topical hidden genome: discovering latent cancer mutational topics using a Bayesian multilevel context-learning approach

S Chakraborty, Z Guan, CB Begg, R Shen - Biometrics, 2024 - academic.oup.com
Inferring the cancer-type specificities of ultra-rare, genome-wide somatic mutations is an
open problem. Traditional statistical methods cannot handle such data due to their ultra-high …

Identifying somatic fingerprints of cancers defined by germline and environmental risk factors

S Chakraborty, Z Guan, CE Kostrzewa… - Genetic …, 2024 - Wiley Online Library
Numerous studies over the past generation have identified germline variants that increase
specific cancer risks. Simultaneously, a revolution in sequencing technology has permitted …