Iron oxide nanoparticles in regenerative medicine and tissue engineering

RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …

Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain

JR Wu, Y Hernandez, KF Miyasaki, EJ Kwon - Advanced drug delivery …, 2023 - Elsevier
The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …

Nanomaterials alleviating redox stress in neurological diseases: mechanisms and applications

Y Jiang, Y Kang, J Liu, S Yin, Z Huang… - Journal of …, 2022 - Springer
Overproduced reactive oxygen and reactive nitrogen species (RONS) in the brain are
involved in the pathogenesis of several neurological diseases, such as Alzheimer's disease …

Sex as an important factor in nanomedicine

MJ Hajipour, H Aghaverdi, V Serpooshan… - Nature …, 2021 - nature.com
Nanomedicine has demonstrated substantial potential to improve the quality and efficacy of
healthcare systems. Although the promise of nanomedicine to transform conventional …

Sex-based differences of antioxidant enzyme nanoparticle effects following traumatic brain injury

AW Tarudji, HA Miller, ET Curtis, CL Porter… - Journal of Controlled …, 2023 - Elsevier
Following traumatic brain injury (TBI), reactive oxygen species (ROS) are released in
excess, causing oxidative stress, carbonyl stress, and cell death, which induce the additional …

A focus on “bio” in bio–nanoscience: the impact of biological factors on nanomaterial interactions

C Cortez‐Jugo, E Czuba‐Wojnilowicz… - Advanced …, 2021 - Wiley Online Library
Bio–nanoscience research encompasses studies on the interactions of nanomaterials with
biological structures or what is commonly referred to as the biointerface. Fundamental …

Antioxidant thioether core-crosslinked nanoparticles prevent the bilateral spread of secondary injury to protect spatial learning and memory in a controlled cortical …

AW Tarudji, CC Gee, SM Romereim, AJ Convertine… - Biomaterials, 2021 - Elsevier
The secondary phase of traumatic brain injury (TBI) is partly caused by the release of excess
reactive oxygen species (ROS) from the primary injury. However, there are currently no …

Traumatic brain injury induces TDP-43 mislocalization and neurodegenerative effects in tissue distal to the primary injury site in a non-transgenic mouse

GR Bjorklund, J Wong, D Brafman, R Bowser… - Acta neuropathologica …, 2023 - Springer
Traumatic brain injury (TBI) initiates tissue and cellular damage to the brain that is
immediately followed by secondary injury sequalae with delayed and continual damage …

Sex as a biological variable in tissue engineering and regenerative medicine

JB Allen, C Ludtka, BD James - Annual review of biomedical …, 2023 - annualreviews.org
Although sex differences have been noted in cellular function and behavior, therapy efficacy,
and disease incidence and outcomes, the adoption of sex as a biological variable in tissue …

Claudin-1-targeted nanoparticles for delivery to aging-induced alterations in the blood–brain barrier

BA Bony, AW Tarudji, HA Miller, S Gowrikumar, S Roy… - Acs Nano, 2021 - ACS Publications
Aging-induced alterations to the blood–brain barrier (BBB) are increasingly being seen as a
primary event in chronic progressive neurological disorders that lead to cognitive decline …