Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer

I Umelo, A Noeparast, G Chen, M Renard… - …, 2015 - pmc.ncbi.nlm.nih.gov
Somatic mutations found within the tyrosine kinase domain (TKD) of the human epidermal
growth factor (HER) family of receptors have been implicated in the development and …

Modeling human genome (3D) using linear & nearest interpolation

A Kumar, V Verma - 2022 8th International Conference on …, 2022 - ieeexplore.ieee.org
This paper explains the solution of problem related to representation of structure of human
genome data into 3 dimensional structure, to extract and represent patterns in human …

Overview of genomic tools for circular visualization in the next-generation genomic sequencing era

A Parveen, S Khurana, A Kumar - Current genomics, 2019 - ingentaconnect.com
After human genome sequencing and rapid changes in genome sequencing methods, we
have entered into the era of rapidly accumulating genome-sequencing data. This has …

Lexicon Visualization Library and JavaScript for scientific data visualization

I Tanyalcin, C Al Assaf, J Ferte, F Ancien… - … in Science & …, 2018 - ieeexplore.ieee.org
It's becoming increasingly challenging to efficiently visualize and extract useful insight from
complex and big data sets. JavaScript stands out as a suitable programming choice that …

Relationships Among Human Genome Graph Elements Using Clusters Detection

A Kumar, V Verma - International Conference on Advanced Informatics for …, 2021 - Springer
Advancements in genome sequencing technologies have generated massive amount of
biological data. Data driven research leads to better understanding and interpretation of …

Convert your favorite protein modeling program into a mutation predictor:“MODICT”

I Tanyalcin, K Stouffs, D Daneels, C Al Assaf… - BMC …, 2016 - Springer
Background Predict whether a mutation is deleterious based on the custom 3D model of a
protein. Results We have developed modict, a mutation prediction tool which is based on …

Indoril: An I-PV Add-On for Visualization of Point Mutations on 3D Cartesian Coordinates

I Tanyalcin, J Ferte, T Khan, CA Assaf - bioRxiv, 2017 - biorxiv.org
One of the main goals of proteomics is to understand how point mutations impact on the
protein structure. Visualization and clustering of point mutations on user-defined 3 …