Treatment of plague: promising alternatives to antibiotics

AP Anisimov, KK Amoako - Journal of medical …, 2006 - microbiologyresearch.org
Plague still poses a significant threat to human health, and interest has been renewed
recently in the possible use of Yersinia pestis as a biological weapon by terrorists. The …

Adhesive organelles of Gram-negative pathogens assembled with the classical chaperone/usher machinery: structure and function from a clinical standpoint

V Zav'yalov, A Zavialov, G Zav'yalova… - FEMS microbiology …, 2010 - academic.oup.com
This review summarizes current knowledge on the structure, function, assembly and
biomedical applications of the superfamily of adhesive fimbrial organelles exposed on the …

Bcipep: a database of B-cell epitopes

S Saha, M Bhasin, GPS Raghava - BMC genomics, 2005 - Springer
Background Bcipep is a database of experimentally determined linear B-cell epitopes of
varying immunogenicity collected from literature and other publicly available databases …

Interpreting the B-cell receptor repertoire with single-cell gene expression using Benisse

Z Zhang, WY Chang, K Wang, Y Yang… - Nature Machine …, 2022 - nature.com
B-cell receptors (BCRs) are a crucial player in the development and activation of B cells, and
their mature forms are secreted as antibodies, which execute functions such as the …

Effective plague vaccination via oral delivery of plant cells expressing F1-V antigens in chloroplasts

PA Arlen, M Singleton, JJ Adamovicz, Y Ding… - Infection and …, 2008 - Am Soc Microbiol
The chloroplast bioreactor is an alternative to fermentation-based systems for production of
vaccine antigens and biopharmaceuticals. We report here expression of the plague F1-V …

A fully synthetic four‐component antitumor vaccine consisting of a mucin glycopeptide antigen combined with three different T‐helper‐cell epitopes

B Palitzsch, S Hartmann, N Stergiou… - Angewandte Chemie …, 2014 - Wiley Online Library
In a new concept of fully synthetic vaccines, the role of T‐helper cells is emphasized. Here, a
synthetic antitumor vaccine consisting of a diglycosylated tumor‐associated MUC1 …

An anthrax subunit vaccine candidate based on protective regions of Bacillus anthracis protective antigen and lethal factor

LW Baillie, TB Huwar, S Moore, G Mellado-Sanchez… - Vaccine, 2010 - Elsevier
Studies have confirmed the key role of Bacillus anthracis protective antigen (PA) in the US
and UK human anthrax vaccines. However, given the tripartite nature of the toxin, other …

Yersinia pestis Antigen F1 but Not LcrV Induced Humoral and Cellular Immune Responses in Humans Immunized with Live Plague Vaccine—Comparison of …

VA Feodorova, AM Lyapina, MA Khizhnyakova… - Vaccines, 2020 - mdpi.com
The recent progress in immunoinformatics provided the basis for an accelerated
development of target-specific peptide vaccines as an alternative to the traditional vaccine …

Robust Th1 cellular and humoral responses generated by the Yersinia pestis rF1-V subunit vaccine formulated to contain an agonist of the CD137 pathway do not …

W Bowen, L Batra, AR Pulsifer, ES Yolcu, MB Lawrenz… - Vaccine, 2019 - Elsevier
Yersinia pestis is the causative agent of plague and is a re-emerging pathogen that also has
the potential as a biological weapon, necessitating the development of a preventive vaccine …

Development of Yersinia pestis F1 antigen-loaded microspheres vaccine against plague

S Huang, IH Li, P Hong, M Yeh - International journal of …, 2014 - Taylor & Francis
Yersinia pestis F1 antigen-loaded poly (DL-lactide-co-glycolide)/polyethylene glycol
(PEG)(PLGA/PEG) microspheres were produced using a water-in-oil-in-water …