T cell responses to SARS-CoV-2

A Sette, J Sidney, S Crotty - Annual review of immunology, 2023 - annualreviews.org
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic

A Bertoletti, N Le Bert, AT Tan - Immunity, 2022 - cell.com
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, multiple severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …

Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis

A Grifoni, T Alonzi, G Alter, DMC Noonan… - Frontiers in …, 2023 - frontiersin.org
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

[HTML][HTML] Defending against SARS-CoV-2: The T cell perspective

P Almendro-Vázquez, R Laguna-Goya… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …

[HTML][HTML] Recent updates on correlates of vaccine-induced protection

SA Plotkin - Frontiers in Immunology, 2023 - frontiersin.org
Correlates of protection are key for vaccine development against any pathogen. In this paper
we summarize recent information about correlates for vaccines against dengue, Ebola …

Silent battles: immune responses in asymptomatic SARS-CoV-2 infection

N Le Bert, T Samandari - Cellular & Molecular Immunology, 2024 - nature.com
SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …

[HTML][HTML] Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences

A Aiello, S Najafi-Fard, D Goletti - Frontiers in Immunology, 2023 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …

[HTML][HTML] T cell control of SARS-CoV-2: When, which, and where?

MO Diniz, MK Maini, L Swadling - Seminars in Immunology, 2023 - Elsevier
Efficient immune protection against viruses such as SARS-CoV-2 requires the coordinated
activity of innate immunity, B and T cells. Accumulating data point to a critical role for T cells …

Assessing SARS-CoV-2-specific T-cell reactivity in late convalescents and vaccinees: Comparison and combination of QuantiFERON and activation-induced marker …

A Gatti, G Zizzo, M De Paschale, A Tamburello… - Plos one, 2023 - journals.plos.org
Objectives Monitoring of SARS-CoV-2 spread and vaccination strategies have relied on
antibody (Ab) status as a correlate of protection. We used QuantiFERON™(QFN) and …

Correlative CD4 and CD8 T-cell immunodominance in humans and mice: Implications for preclinical testing

TAP Neto, J Sidney, A Grifoni, A Sette - Cellular & Molecular …, 2023 - nature.com
Antigen-specific T-cell recognition is restricted by Major Histocompatibility Complex (MHC)
molecules, and differences between CD4 and CD8 immunogenicity in humans and animal …