The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …

Although the genetic basis of many kidney diseases is being rapidly elucidated, their
experimental study remains problematic owing to the lack of suitable models. The fruitfly …

Maintenance of renal function and fluid transport are essential for vertebrates and
invertebrates to adapt to physiological and pathological challenges. Human patients with …

Kidney disease is highly prevalent and affects approximately 850 million people worldwide.
It is also associated with high morbidity and mortality, and current therapies are incurable …

Cordyceps militaris may show good promise in protecting against chronic kidney disease
(CKD) but the molecular mechanism remains unclear. CKD risk is associated with the Toll …

Adult Drosophila Malpighian tubules have low rates of cell turnover but are vulnerable to
damage caused by stones, like their mammalian counterparts, kidneys. We show that …

Ticks are important disease vectors, as they transmit a variety of human and animal
pathogens worldwide. Symbionts that coevolved with ticks confer crucial benefits to their …

Paraneoplastic syndromes occur in cancer patients and originate from dysfunction of organs
at a distance from the tumor or its metastasis. A wide range of organs can be affected in …

The Malpighian (renal) tubule is capable of transporting fluid at remarkable rates. This
review will focus on recent insights into the mechanisms by which these high rates are …

Polyploidy, a cell status defined as more than two sets of genomic DNA, is a conserved
strategy across species that can increase cell size and biosynthetic production, but the …