Astrocytes are a population of cells with distinctive morphological and functional
characteristics that differ within specific areas of the brain. Postnatally, astrocyte progenitors …

Glial cells have a variety of functions in the brain, ranging from immune defense against
external and endogenous hazardous stimuli, regulation of synaptic formation, calcium …

Compelling evidence from basic molecular biology has demonstrated the dual roles of
microglia in the pathogenesis of Alzheimer's disease (AD). On one hand, microglia are …

The increasing prevalence of multidrug-resistant bacterial infections necessitates the
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …

Several different receptor proteins have been identified that bind monomeric, oligomeric, or
fibrillar forms of amyloid-β (Aβ)." Good" receptors internalize Aβ or promote its transcytosis …

Amyloid β (Aβ) plays a pivotal role in the progression of Alzheimer's disease (AD) through its
neurotoxic and inflammatory effects. On one hand, Aβ binds to microglia and activates them …

Alzheimer's disease (AD) is a highly complex neurodegenerative disorder of the aged that
has multiple factors which contribute to its etiology in terms of initiation and progression. This …

The formyl peptide receptor 2 (FPR2) is a remarkably versatile transmembrane protein
belonging to the G-protein coupled receptor (GPCR) family. FPR2 is activated by an array of …

Alzheimer's disease (AD) is increasing in prevalence with the aging population. Deposition
of amyloid‐β (Aβ) in the brain of AD patients is a hallmark of the disease and is associated …

The brain microenvironment is continuously monitored by microglia with the detection of
apoptotic cells or pathogens being rapidly followed by their phagocytosis to prevent …