Orthopaedic device implants play a crucial role in restoring functionality to patients suffering
from debilitating musculoskeletal diseases or to those who have experienced traumatic …

The formation of biofilms is closely associated with persistent and chronic infections, and
physiological heterogeneity such as pH and oxygen gradients renders biofilms highly …

Host–guest complexation-based suprasomes successfully deliver benzimidazolium
amphiphiles. β-CD and Zn2+ or an acidic environment act as the stimuli for the assembly …

The administration of therapeutics using bioconjugation has been mainly limited to drugs
containing amine, alcohol, or thiol functional groups. Here, we report a general procedure …

Antimicrobial resistance (AMR) has emerged as a global health challenge, sparking
worldwide interest in exploring the antimicrobial potential of natural compounds as an …

The countermeasure of biofilm infections leaving a challenge due to a dense antibiotic-
resistant barrier formed by extracellular polymeric substances (EPS). Although antibiotic …

P-glycoprotein (Pgp) is known for its dichotomous roles as both a safeguarding efflux
transporter against xenobiotics and as a catalyst for multidrug resistance. Given the …

Biofilm recalcitrance, which enables bacteria to survive deep within the body under
antimicrobial treatment, leading to persistent infections by reducing the penetration of …

This study reports the utilization of a Curcumin-Exopolysaccharide (Cur-EPS) micellar
bioconjugate comprising acid-labile ester bond as a carrier for ciprofloxacin (Cip) to improve …

Antimicrobial resistance (AMR) has become a worldwide health problem. Consequently,
there is a global interest in the study of the antimicrobial activity of natural compounds as an …