Rapidly evolving RNA viruses continuously produce viral minority variants following infection that can quickly spread and become dominant variants if they are drug-resistant or …
Next-generation sequencing (NGS) technologies experienced giant leaps in recent years. Short read samples reach millions of reads, and the number of samples has been growing …
The deep coverage offered by next-generation sequencing (NGS) technology has facilitated the reconstruction of intra-host RNA viral populations at an unprecedented level of detail …
RNA viruses mutate at extremely high rates, forming an intra-host viral population of closely related variants, which allows them to evade the host's immune system and makes them …