miRNAs as potential game-changers in melanoma: a comprehensive review
Melanoma is the sixth most frequent malignancy. It represents 1.7% of all cancer cases
worldwide. Many risk factors are associated with melanoma including ultraviolet radiation …
worldwide. Many risk factors are associated with melanoma including ultraviolet radiation …
The evolving modern management of brain metastasis
The incidence of brain metastases is increasing as cancer therapies improve and patients
live longer, providing new challenges to the multidisciplinary teams that care for these …
live longer, providing new challenges to the multidisciplinary teams that care for these …
An overview of ADAM9: structure, activation, and regulation in human diseases
ADAM9 (A disintegrin and a metalloprotease 9) is a membrane-anchored protein that
participates in a variety of physiological functions, primarily through the disintegrin domain …
participates in a variety of physiological functions, primarily through the disintegrin domain …
[HTML][HTML] Identification of theranostic factors for patients developing metastasis after surgery for early-stage lung adenocarcinoma
WC Cheng, CY Chang, CC Lo, CY Hsieh, TT Kuo… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Lung adenocarcinoma (LUAD) is an aggressive disease with high propensity of
metastasis. Among patients with early-stage disease, more than 30% of them may relapse or …
metastasis. Among patients with early-stage disease, more than 30% of them may relapse or …
EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study
Z Hao, D Guo - BMC cancer, 2019 - Springer
Background Glioma is one of the most common type of primary central nervous system
tumors. EGFR mutation, a common alteration occurs in various tumors, is not brought to the …
tumors. EGFR mutation, a common alteration occurs in various tumors, is not brought to the …
Inhibition of ADAM9 promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy
Kirsten rat sarcoma virus (KRAS) signaling drives pancreatic ductal adenocarcinoma
(PDAC) malignancy, which is an unmet clinical need. Here, we identify a disintegrin and …
(PDAC) malignancy, which is an unmet clinical need. Here, we identify a disintegrin and …
Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension
K Goel, N Egersdorf, A Gill, D Cao, SD Collum… - Respiratory …, 2022 - Springer
Background Despite causing increased morbidity and mortality, pulmonary hypertension
(PH) in chronic obstructive pulmonary disease (COPD) patients (COPD-PH) lacks treatment …
(PH) in chronic obstructive pulmonary disease (COPD) patients (COPD-PH) lacks treatment …
The pleiotropic roles of ADAM9 in the biology of solid tumors
VO Oria, P Lopatta, O Schilling - Cellular and Molecular Life Sciences, 2018 - Springer
A disintegrin and a metalloprotease (ADAM) 9 is a metzincin cell-surface protease involved
in several biological processes such as myogenesis, fertilization, cell migration …
in several biological processes such as myogenesis, fertilization, cell migration …
ADAM 9 contributes to vascular invasion in pancreatic ductal adenocarcinoma
VO Oria, P Lopatta, T Schmitz, BT Preca… - Molecular …, 2019 - Wiley Online Library
A disintegrin and a metalloprotease (ADAM)‐9 is a metzincin cell‐surface protease with
strongly elevated expression in solid tumors, including pancreatic ductal adenocarcinoma …
strongly elevated expression in solid tumors, including pancreatic ductal adenocarcinoma …
Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer
Circular RNAs (circRNAs) constitute a recently identified category of closed continuous loop
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …