Highlights•Liquid-liquid phase separation underlies the formation of membraneless
organelles within cells.•Theory and molecular simulations help to relate interactions at the …

Amyloid fibrils are β-sheet rich protein aggregates that are strongly associated with various
neurodegenerative diseases. Raman spectroscopy has been broadly utilized to investigate …

Liquid–liquid phase separation (LLPS) of proteins and other biomolecules play a critical role
in the organization of extracellular materials and membrane‐less compartmentalization of …

Hydrophobic interactions are involved in and believed to be the fundamental driving force of
many chemical and biological phenomena in aqueous environments. This review focuses …

For disordered proteins, the dimensions of the chain are an important property that is
sensitive to environmental conditions. We have used single-molecule Förster resonance …

The hydrophobic effect is the main driving force in protein folding. One can estimate the
relative strength of this hydrophobic effect for each amino acid by mining a large set of …

The process of freezing proteins is widely used in applications ranging from processing and
storage of biopharmaceuticals to cryo-EM analysis of protein complexes. The formation of an …

The hydrophobic effect is considered the main driving force for protein folding and plays an
important role in the stability of those biomolecules. Cold denaturation, where the native …

Biological activity requires a solvent that can provide a suitable environment, which satisfies
the twin need for stability and the ability to change. Among all the solvents water plays the …

According to our recent studies on hydrophobic interactions, this work is devoted to
investigate the temperature effects on hydrophobic interactions. Regarding to hydrophobic …