Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million
new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine …

While a third of the world carries the burden of tuberculosis, disease control has been
hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective …

Despite over a century of research, Mycobacterium tuberculosis (Mtb), the causative agent of
tuberculosis (TB), continues to kill 1.5 million people annually. Though less than 10% of …

Induction of Th1 (cell-mediated) immunity and associated production of IFN-γ by CD4+ T
cells has been widely used as a marker of protective immunity against tuberculosis (TB) …

Variability in the susceptibility to infectious disease and its clinical manifestation can be
determined by variation in the environment and by genetic variation in the pathogen and the …

In this review, we discuss how IgG antibodies can modulate inflammatory signaling during
viral infections with a focus on CD16a‐mediated functions. We describe the structural …

Over the past decade, a wealth of experimental evidence has accumulated supporting the
importance of Fc receptor (FcR) ligation in antibody‐mediated pathology and protection in …

Mycobacterium tuberculosis (Mtb) resides in a quarter of the world's population and is the
causative agent for tuberculosis (TB), the most common infectious reason of death in …

Fcγ receptors are a family of cell–surface receptors that are expressed by a host of different
innate and adaptive immune cells, and mediate inflammatory responses by binding the Fc …

Fc gamma receptors (FcγR) are cell surface glycoproteins which trigger specific effector-cell
responses when cross-linked with the Fc portions of immunoglobulin (IgG) antibodies …