[HTML][HTML] Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis
R Kandimalla, PH Reddy - Biochimica et Biophysica Acta (BBA)-Molecular …, 2016 - Elsevier
Mitochondria play a large role in neuronal function by constantly providing energy,
particularly at synapses. Recent studies suggest that amyloid beta (Aβ) and phosphorylated …
particularly at synapses. Recent studies suggest that amyloid beta (Aβ) and phosphorylated …
Amyloid beta modulators and neuroprotection in Alzheimer's disease: a critical appraisal
CS Kuruva, PH Reddy - Drug discovery today, 2017 - Elsevier
Highlights•Multiple cellular changes have been identified as being involved in AD
pathogenesis.•Studies concluded that abnormal APP processing causes Aβ-induced …
pathogenesis.•Studies concluded that abnormal APP processing causes Aβ-induced …
ABCA1‐mediated cholesterol efflux capacity to cerebrospinal fluid is reduced in patients with mild cognitive impairment and Alzheimer's disease
HN Yassine, Q Feng, J Chiang… - Journal of the …, 2016 - Am Heart Assoc
Background Animal and human studies indicate that ABCA1‐mediated cholesterol transport
is important in Alzheimer's disease (AD). We hypothesized that the efficiency of …
is important in Alzheimer's disease (AD). We hypothesized that the efficiency of …
A triple network connectivity study of large-scale brain systems in cognitively normal APOE4 carriers
The triple network model, consisting of the central executive network (CEN), salience
network (SN) and default mode network (DMN), has been recently employed to understand …
network (SN) and default mode network (DMN), has been recently employed to understand …
[HTML][HTML] Quantification of total apolipoprotein E and its specific isoforms in cerebrospinal fluid and blood in Alzheimer's disease and other neurodegenerative diseases
A targeted mass spectrometric assay was developed for identification and quantification of
apoE isoforms (apoE2, E3 and E4), and it was utilized for screening of samples from AD …
apoE isoforms (apoE2, E3 and E4), and it was utilized for screening of samples from AD …
HDL-cholesterol and apolipoproteins in relation to dementia
Associations in cross-sectional studies are not always indicative of a prospective
relationship. Large studies find that plasma HDL-C and apoE are inversely associated with …
relationship. Large studies find that plasma HDL-C and apoE are inversely associated with …
APOE4: a culprit for the vulnerability of COVID-19 in Alzheimer's patients
A Goyal, PS Kushwah, N Agrawal… - Current Neurovascular …, 2023 - ingentaconnect.com
Apolipoprotein E4 (APOE4) is one of the primary genetic risk factors for late-onset of
Alzheimer's disease (AD). While its primary function is to transport cholesterol, it also …
Alzheimer's disease (AD). While its primary function is to transport cholesterol, it also …
Meta-analysis of apolipoprotein E levels in the cerebrospinal fluid of patients with Alzheimer's disease
The possible association between Apolipoprotein E (ApoE) levels in the cerebrospinal fluid
(CSF) and Alzheimer's disease (AD) has been studied extensively. However, previous …
(CSF) and Alzheimer's disease (AD) has been studied extensively. However, previous …
Abnormal changes of brain cortical anatomy and the association with plasma MicroRNA107 level in amnestic mild cognitive impairment
MicroRNA107 (Mir107) has been thought to relate to the brain structure phenotype of
Alzheimer's disease. In this study, we evaluated the cortical anatomy in amnestic mild …
Alzheimer's disease. In this study, we evaluated the cortical anatomy in amnestic mild …
CSF ubiquitin as a specific biomarker in Alzheimer's disease
RJ Kandimalla, R Anand… - Current Alzheimer …, 2014 - ingentaconnect.com
Alzheimer's disease (AD) is the most common cause of dementia worldwide. Although,
many putative biomarkers are reported for AD, only a few have been validated in the clinical …
many putative biomarkers are reported for AD, only a few have been validated in the clinical …