Epigenetic modification and BRAF gene mutation in thyroid carcinoma

G Huang, J Chen, J Zhou, S Xiao, W Zeng, J Xia… - Cancer cell …, 2021 - Springer
Thyroid cancer remains the most prevailing endocrine malignancy, and a progressively
increasing incidence rate has been observed in recent years, with 95% of thyroid cancer …

The role of vitamin C in epigenetic cancer therapy

SU Mikkelsen, L Gillberg, J Lykkesfeldt… - Free Radical Biology and …, 2021 - Elsevier
The role of vitamin C in the treatment of cancer has been subject to controversy for decades.
Within the past 10 years, mechanistic insight into the importance of vitamin C in epigenetic …

Multi-omics analysis identified TMED2 as a shared potential biomarker in six subtypes of human cancer

N Sial, S Saeed, M Ahmad, Y Hameed… - … journal of general …, 2021 - Taylor & Francis
Introduction Cancer is one of the most common malignancies and the leading cause of
death worldwide. As a member of the transmembrane emp24 domain (Tmed)/p24 family of …

The role of epigenetic methylations in thyroid Cancer

X Yu, H Zhang, H Zhang, C Hou, X Wang, P Gu… - World Journal of …, 2024 - Springer
Thyroid cancer (TC) represents one of the most prevalent endocrine malignancies, with a
rising incidence worldwide. Epigenetic alterations, which modify gene expression without …

[HTML][HTML] Development and Evaluation of Docetaxel-Loaded Nanostructured Lipid Carriers for Skin Cancer Therapy

FI Cocoș, V Anuța, L Popa, MV Ghica, MA Nica… - Pharmaceutics, 2024 - mdpi.com
This study focuses on the design, characterization, and optimization of nanostructured lipid
carriers (NLCs) loaded with docetaxel for the treatment of skin cancer. Employing a …

[HTML][HTML] Ten-eleven translocation proteins (TETs): tumor suppressors or tumor enhancers?

C Ma, H Seong, Y Liu, X Yu, S Xu, Y Li - Frontiers in Bioscience …, 2021 - imrpress.com
The epigenetic memory stored in the dynamic modifications, such as base modifications of
cytosine (C) in DNA, including methylation/hydroxymethylation/demethylation, causes …

High-dose vitamin C: preclinical evidence for tailoring treatment in cancer patients

M Giansanti, T Karimi, I Faraoni, G Graziani - Cancers, 2021 - mdpi.com
Simple Summary Vitamin C is an indispensable micronutrient in the human diet due to the
multiple functions it carries out in the body. Reports of clinical studies have indicated that …

Resveratrol modulation of apoptosis and cell cycle response to cisplatin in head and neck cancer cell lines

M Bostan, M Mihaila, GG Petrica-Matei, N Radu… - International Journal of …, 2021 - mdpi.com
In head and neck cancers, the effectiveness of cisplatin (CisPt) treatment is limited by its
toxicity, especially when higher doses are necessary, and the possible occurrence of …

Long non-coding RNA CRNDE suppressing cell proliferation is regulated by DNA methylation in chronic lymphocytic leukemia

J Ni, J Hong, Q Li, Q Zeng, R Xia - Leukemia Research, 2021 - Elsevier
Long non-coding RNA CRNDE and DNA methylation play a vital role in the occurrence and
development of chronic lymphocytic leukemia (CLL). This study attempted to investigate the …

Identifying M1 macrophage-related genes through a co-expression network to construct a four-gene risk-scoring model for predicting thyroid cancer prognosis

G Zhuang, Y Zeng, Q Tang, Q He, G Luo - Frontiers in Genetics, 2020 - frontiersin.org
Macrophages are key innate immune cells in the tumor microenvironment that regulate
primary tumor growth, vascularization, metastatic spread and response to therapies …