Fracture risk reduction and safety by osteoporosis treatment compared with placebo or active comparator in postmenopausal women: systematic review, network meta …

MN Händel, I Cardoso, C Von Bülow, JF Rohde… - bmj, 2023 - bmj.com
Objective To review the comparative effectiveness of osteoporosis treatments, including the
bone anabolic agents, abaloparatide and romosozumab, on reducing the risk of fractures in …

Comparative effectiveness of pharmacologic treatments to prevent fractures: an updated systematic review

CJ Crandall, SJ Newberry, A Diamant… - Annals of internal …, 2014 - acpjournals.org
Background: Osteoporosis is a major contributor to the propensity to fracture among older
adults, and various pharmaceuticals are available to treat it. Purpose: To update a review …

Treatment of low bone density or osteoporosis to prevent fractures in men and women: a clinical practice guideline update from the American College of Physicians

A Qaseem, MA Forciea, RM McLean… - Annals of internal …, 2017 - acpjournals.org
Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A
Clinical Practice Guideline Update From the American College of Physicians | Annals of Internal …

[HTML][HTML] Interpreting indirect treatment comparisons and network meta-analysis for health-care decision making: report of the ISPOR Task Force on Indirect Treatment …

JP Jansen, R Fleurence, B Devine, R Itzler, A Barrett… - Value in health, 2011 - Elsevier
Evidence-based health-care decision making requires comparisons of all relevant
competing interventions. In the absence of randomized, controlled trials involving a direct …

Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women

GA Wells, SC Hsieh, C Zheng… - Cochrane Database …, 2022 - cochranelibrary.com
Background Osteoporosis is an abnormal reduction in bone mass and bone deterioration
leading to increased fracture risk. Risedronate belongs to the bisphosphonate class of drugs …

Bisphosphonates for the prevention and treatment of osteoporosis

S Maraka, KA Kennel - Bmj, 2015 - bmj.com
Osteoporosis is a systemic skeletal disorder characterized by bone loss, which leads to
impaired bone strength and an increased risk of fractures. Two million fractures are …

Uncertainty in treatment rankings: reanalysis of network meta-analyses of randomized trials

L Trinquart, N Attiche, A Bafeta, R Porcher… - Annals of internal …, 2016 - acpjournals.org
Background: Ranking of interventions is one of the most appealing elements of network
meta-analysis. There is, however, little evidence about the reliability of these rankings …

Exercise and fractures in postmenopausal women. Final results of the controlled Erlangen Fitness and Osteoporosis Prevention Study (EFOPS)

W Kemmler, M Bebenek, M Kohl… - Osteoporosis …, 2015 - Springer
The EFOPS trial clearly established the positive effect of long-term exercise on clinical low-
trauma fractures in postmenopausal women at risk. Bearing in mind that the complex anti …

Emerging therapeutic opportunities for skeletal restoration

M Kawai, UI Mödder, S Khosla, CJ Rosen - Nature reviews Drug …, 2011 - nature.com
Osteoporosis, a syndrome characterized by thin bones and fractures, has become more
prevalent in both women and men. Established therapies for treating this disorder consist …

Interaction between bone and muscle in older persons with mobility limitations

L Ferrucci, M Baroni, A Ranchelli… - Current …, 2014 - ingentaconnect.com
Aging is associated with a progressive loss of bone-muscle mass and strength. When the
decline in mass and strength reaches critical thresholds associated with adverse health …