Ki67, PCNA, and MCM proteins: Markers of proliferation in the diagnosis of breast cancer
M Juríková, Ľ Danihel, Š Polák, I Varga - Acta histochemica, 2016 - Elsevier
The proliferative activity of tumour cells represents an important prognostic marker in the
diagnosis of cancer. One of the methods for assessing the proliferative activity of cells is the …
diagnosis of cancer. One of the methods for assessing the proliferative activity of cells is the …
[HTML][HTML] The role of Anaphase Promoting Complex activation, inhibition and substrates in cancer development and progression
Abstract The Anaphase Promoting Complex (APC), a multi-subunit ubiquitin ligase,
facilitates mitotic and G1 progression, and is now recognized to play a role in maintaining …
facilitates mitotic and G1 progression, and is now recognized to play a role in maintaining …
[HTML][HTML] MCM2, MCM4, and MCM6 in breast cancer: clinical utility in diagnosis and prognosis
Breast cancer is a heterogeneous disease comprising the estrogen receptor (ER)–positive
luminal subtype which is subdivided into luminal A and luminal B and ER-negative breast …
luminal subtype which is subdivided into luminal A and luminal B and ER-negative breast …
Clinical proteomics for solid organ tissues
WS Phipps, MR Kilgore, JJ Kennedy… - Molecular & Cellular …, 2023 - ASBMB
The evaluation of biopsied solid organ tissue has long relied on visual examination using a
microscope. Immunohistochemistry is critical in this process, labeling and detecting cell …
microscope. Immunohistochemistry is critical in this process, labeling and detecting cell …
Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
M Andrea, T Weinschenk, V Goldfinger… - US Patent …, 2019 - Google Patents
The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …
immunotherapeutic methods. In particular, the present invention relates to the immuno …
Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
M Andrea, T Weinschenk, V Goldfinger… - US Patent …, 2019 - Google Patents
The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …
immunotherapeutic methods. In particular, the present invention relates to the immuno …
[HTML][HTML] MCM2: an alternative to Ki-67 for measuring breast cancer cell proliferation
Breast cancer is a heterogeneous disease comprising a diversity of tumor subtypes that
manifest themselves in a wide variety of clinical, pathological, and molecular features. One …
manifest themselves in a wide variety of clinical, pathological, and molecular features. One …
Varying outcomes of triple-negative breast cancer in different age groups–prognostic value of clinical features and proliferation
H Vihervuori, K Korpinen, TA Autere, H Repo… - Breast Cancer Research …, 2022 - Springer
Purpose Triple-negative breast cancer (TNBC) is an aggressive disease lacking specific
biomarkers to guide treatment decisions. We evaluated the combined prognostic impact of …
biomarkers to guide treatment decisions. We evaluated the combined prognostic impact of …
Computational assessment of MCM2 transcriptional expression and identification of the prognostic biomarker for human breast cancer
Abstract Minichromosome maintenance protein 2 (MCM2) is a highly conserved protein from
the MCM protein family that plays an important role in eukaryotic DNA replication as well as …
the MCM protein family that plays an important role in eukaryotic DNA replication as well as …
Minichromosome maintenance protein 2 correlates with the malignant status and regulates proliferation and cell cycle in lung squamous cell carcinoma
W Wu, X Wang, C Shan, Y Li, F Li - OncoTargets and therapy, 2018 - Taylor & Francis
Background Minichromosome maintenance protein 2 (MCM2), which is a member of MCM
family, has been found to be a relevant marker for progression and prognosis in a variety of …
family, has been found to be a relevant marker for progression and prognosis in a variety of …