Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …

Prostate cancer has a long disease history and a wide variety and uncertainty in individual
patients' clinical progress. In recent years, we have seen a revolutionary advance in both …

Cancer stem-like cells (CSCs) contribute to cancer metastasis, drug resistance and tumor
relapse, yet how amino acid metabolism promotes CSC maintenance remains exclusive …

The severe form of COVID-19 has significant sex disparities, with high fatalities commonly
reported among males than females. The incidence of COVID-19 has also been higher in …

The ETS-related gene (ERG) is proto-oncogene that is classified as a member of the ETS
transcription factor family, which has been found to be consistently overexpressed in about …

The use of already-approved drugs to treat new or alternative diseases has proved to be
beneficial in medicine, because it reduces both drug development costs and timelines. Most …

Prostate cancer is one of the most frequent male-specific malignancies globally, with
advanced disease stages associated with substantial morbidity and fatality rates. Various …

Prostate cancer is one of the most prevalent malignant tumors in men worldwide, and early
diagnosis is essential to improve patient survival. This review provides a comprehensive …

Cancer stem cells (CSCs) represent a small subset of slowly dividing cells with tumor-
initiating ability. They can self-renew and differentiate into all the distinct cell populations …

Androgens are steroid hormones governing the male reproductive development and
function. As such, androgens and the key mediator of their effects, androgen receptor (AR) …