Comparing feedback strategies for minimizing noise in gene expression event timing

Z Vahdat, KR Ghusinga, A Singh - 2021 29th Mediterranean …, 2021 - ieeexplore.ieee.org
Many cellular events occur when their corresponding regulatory proteins attain critical
thresholds. Can cells schedule such events with precision by controlling the dynamics of the …

Threshold-crossing time statistics for size-dependent gene expression in growing cells

C Nieto, KR Ghusinga… - 2022 American …, 2022 - ieeexplore.ieee.org
Many intracellular events trigger upon attaining critical concentrations of their corresponding
regulatory proteins. How cells ensure precision in the timing of these events is a …

Feedback strategies for threshold crossing of protein levels at a prescribed time

C Nieto, KR Ghusinga, A Singh - 2022 30th Mediterranean …, 2022 - ieeexplore.ieee.org
The timing of diverse cellular processes is based on the instant when the concentration of
regulatory proteins crosses a critical threshold level. Hence, noise mechanisms inherent to …

Regulatory strategies to schedule threshold crossing of protein levels at a prescribed time

C Nieto, KR Ghusinga, A Singh - bioRxiv, 2022 - biorxiv.org
The timing of diverse cellular processes is based on the instant when the concentration of
regulatory proteins crosses a critical threshold level. Hence, noise mechanisms inherent to …

A single-cell approach reveals variation in cellular phage-producing capacities

S Kannoly, G Oken, J Shadan, D Musheyev, K Singh… - bioRxiv, 2021 - biorxiv.org
Virus burst size, a component of viral fitness, is the average number of viral particles
released from a single infected cell. In this study, we estimated bacteriophage lambda (λ) …

Threshold-crossing time statistics for gene expression in growing cells

C Nieto, KR Ghusinga, C Vargas-García, A Singh - bioRxiv, 2022 - biorxiv.org
Many intracellular events are triggered by attaining critical concentrations of their
corresponding regulatory proteins. How cells ensure precision in the timing of the protein …

Feedback autoregulation of gene expression always amplifies noise in timing of threshold crossing

Many cellular events occur when their corresponding regulatory proteins attain critical
thresholds. Can cells schedule such events with precision by controlling the dynamics of the …