Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management

Q Jiang, S Im, JG Wagner, ML Hernandez… - Free Radical Biology and …, 2022 - Elsevier
Abstract γ-Tocopherol (γT) is a major form of vitamin E in the US diet and the second most
abundant vitamin E in the blood and tissues, while α-tocopherol (αT) is the predominant …

Vitamin E in foodstuff: Nutritional, analytical, and food technology aspects

F Zaaboul, YF Liu - … Reviews in Food Science and Food Safety, 2022 - Wiley Online Library
Vitamin E is a group of isoprenoid chromanols with different biological activities. It comprises
eight oil‐soluble compounds: four tocopherols, namely, α‐, β‐, γ‐, and δ‐tocopherols; and …

Vitamin E alpha-and gamma-tocopherol mitigate colitis, protect intestinal barrier function and modulate the gut microbiota in mice

KY Liu, CH Nakatsu, Y Jones-Hall, A Kozik… - Free Radical Biology and …, 2021 - Elsevier
Inflammatory bowel diseases (IBDs) including colitis are intestinal disorders characterized
by chronic inflammation, barrier dysfunction and dysbiosis. Specific forms of vitamin E have …

Metabolism of natural forms of vitamin E and biological actions of vitamin E metabolites

Q Jiang - Free Radical Biology and Medicine, 2022 - Elsevier
Natural forms of vitamin E comprise four tocopherols and four tocotrienols. During the last
twenty years, there have been breakthroughs in our understanding of vitamin E metabolism …

Revisiting the therapeutic potential of tocotrienol

R Ranasinghe, M Mathai, A Zulli - Biofactors, 2022 - Wiley Online Library
The therapeutic potential of the tocotrienol group stems from its nutraceutical properties as a
dietary supplement. It is largely considered to be safe when consumed at low doses for …

[HTML][HTML] Different Roles of Tocopherols and Tocotrienols in Chemoprevention and Treatment of Prostate Cancer

Q Jiang - Advances in Nutrition, 2024 - ncbi.nlm.nih.gov
The vitamin E family contains α-tocopherol (αT), βT, γT, and δT and α-tocotrienol (TE), βTE,
γTE, and δTE. Research has revealed distinct roles of these vitamin E forms in prostate …

Vitamin E delta-tocotrienol and metabolite 13'-carboxychromanol inhibit colitis-associated colon tumorigenesis and modulate gut microbiota in mice

C Yang, Y Zhao, S Im, C Nakatsu, Y Jones-Hall… - The Journal of nutritional …, 2021 - Elsevier
The gut microbiota play important roles in colon cancer. Vitamin E δ-tocotrienol (δTE) and its
metabolite δTE-13′-carboxychromanol (δTE-13′) are known to have cancer-preventive …

[HTML][HTML] Strategies to enhance the solubility and bioavailability of tocotrienols using self-emulsifying drug delivery system

NV Mohamad - Pharmaceuticals, 2023 - mdpi.com
Tocotrienols have higher medicinal value, with multiple sources of evidence showing their
biological properties as antioxidant, anti-inflammatory, and osteoprotective compounds …

Different forms of vitamin E and metabolite 13'-carboxychromanols inhibit cyclooxygenase-1 and its catalyzed thromboxane in platelets, and tocotrienols and 13' …

NY Park, S Im, Q Jiang - The Journal of nutritional biochemistry, 2022 - Elsevier
Abstract Cyclooxygenase (COX-1 and COX-2)-and 5-lipoxygenase (5-LOX)-catalyzed
biosynthesis of eicosanoids play important roles in inflammation and chronic diseases. The …

[HTML][HTML] Different roles of natural forms of vitamin E in chemoprevention and treatment of prostate cancer

Q Jiang - Advances in Nutrition, 2024 - Elsevier
The Vitamin E family contains α-, β-, γ-and δ-tocopherol (αT, βT, γT and δT) and α-, β-, γ-and
δ-tocotrienol (αTE, βTE, γTE and δTE). Research has revealed distinct roles of these vitamin …