The World Health Organization's End TB Strategy prioritizes universal access to an early
diagnosis and comprehensive drug susceptibility testing (DST) for all individuals with …

Given the low treatment success rates of drug-resistant tuberculosis (TB), novel TB drugs are
urgently needed. The landscape of TB treatment has changed considerably over the last …

Transmission-driven multi-/extensively drug resistant (M/XDR) tuberculosis (TB) is the
largest single contributor to human mortality due to antimicrobial resistance. A few major …

Objectives To develop a robust phenotypic antimicrobial susceptibility testing (AST) method
with a correctly set breakpoint for pretomanid (Pa), the most recently approved anti …

Page 1 Catalogue of mutations in Mycobacterium tuberculosis complex and their
association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the deadliest infectious
diseases worldwide. Multidrug and extensively drug-resistant strains are making disease …

Multidrug-resistant (MDR) isolates of Mycobacterium tuberculosis (MTB) remain a primary
global threat to the end of tuberculosis (TB) era. Delamanid (DLM) is a nitro-dihydro …

The emergence of drug resistance continues to afflict TB control where drug resistant strains
have become a global health concern. Contrary to drug-sensitive TB, the treatment of …

Bedaquiline (B), pretomanid (Pa) and linezolid (L) are key components of new regimens for
treating rifampicin-resistant tuberculosis (TB). However, there is limited information on the …

Leprosy is one of the oldest infectious diseases, reported for more than 2000 years. Leprosy
elimination goal as a public health problem set by the World Health Organization, aiming for …