Acute myeloid leukemia (AML) has not benefited from innovative immunotherapies, mainly
because of the lack of actionable immune targets. Using an original proteogenomic …

The Alu element has been a major source of new exons during primate evolution.
Thousands of human genes contain spliced exons derived from Alu elements. However …

Pro-cancer signals are controlled by the expression and transcription of oncogenes.
Transcription of DNA is dependent on the spatially and temporally coordinated interaction …

We previously described the novel zinc finger protein ZKSCAN3 as a new" driver" of colon
cancer progression. To investigate the underlying mechanism and because the predicted …

In an effort to identify the contribution of TEs to bovine genome evolution, the abundance,
distribution and insertional orientation of TEs were examined in all bovine nuclear genes …

The cell fate of primordial germ cells (PGCs) in zebrafish is pre-determined by maternally
deposited germ plasm, which is packaged into ribonucleoprotein complex in oocytes and …

Gypsy/Ty3 retrotransposons, a group of long terminal repeat retrotransposons related to
vertebrate retroviruses, are found in the genome of many fungi, plants, and animals …

The Krüppel-associated box-containing zinc finger gene family (KRAB-ZNF) is one of the
largest gene families of transcriptional factors in the human genome. Although the functions …

Zfp206 (also named as Zscan10) belongs to the subfamily of C 2 H 2 zinc finger transcription
factors, which is characterized by the N-terminal SCAN domain. The SCAN domain …

Jumonij (JMJ)/Jarid2 plays important roles in embryonic development and functions as a
transcriptional repressor. Using yeast two-hybrid screening, we have identified a cofactor of …