The rise of genomics in snake venom research: recent advances and future perspectives

W Rao, K Kalogeropoulos, ME Allentoft… - …, 2022 - academic.oup.com
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …

Phylogenetically diverse diets favor more complex venoms in North American pitvipers

ML Holding, JL Strickland… - Proceedings of the …, 2021 - National Acad Sciences
The role of natural selection in the evolution of trait complexity can be characterized by
testing hypothesized links between complex forms and their functions across species …

When one phenotype is not enough: divergent evolutionary trajectories govern venom variation in a widespread rattlesnake species

G Zancolli, JJ Calvete, MD Cardwell… - … of the Royal …, 2019 - royalsocietypublishing.org
Understanding the origin and maintenance of phenotypic variation, particularly across a
continuous spatial distribution, represents a key challenge in evolutionary biology. For this …

Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake

CF Smith, ZL Nikolakis, K Ivey, BW Perry, DR Schield… - BMC biology, 2023 - Springer
Background Snake venoms are trophic adaptations that represent an ideal model to
examine the evolutionary factors that shape polymorphic traits under strong natural …

[HTML][HTML] Interpopulational variation and ontogenetic shift in the venom composition of Lataste's viper (Vipera latastei, Boscá 1878) from northern Portugal

I Avella, JJ Calvete, L Sanz, W Wüster, F Licata… - Journal of …, 2022 - Elsevier
Lataste's viper (Vipera latastei) is a venomous European viper endemic to the Iberian
Peninsula, recognised as medically important by the World Health Organization. To date, no …

The molecular basis of venom resistance in a rattlesnake‐squirrel predator‐prey system

HL Gibbs, L Sanz, A Pérez, A Ochoa… - Molecular …, 2020 - Wiley Online Library
Understanding how interspecific interactions mould the molecular basis of adaptations in
coevolving species is a long‐sought goal of evolutionary biology. Venom in predators and …

Resistance Is not futile: widespread convergent evolution of resistance to alpha-neurotoxic snake venoms in caecilians (Amphibia: Gymnophiona)

M Mancuso, S Zaman, ST Maddock, RG Kamei… - International Journal of …, 2023 - mdpi.com
Predatory innovations impose reciprocal selection pressures upon prey. The evolution of
snake venom alpha-neurotoxins has triggered the corresponding evolution of resistance in …

New insights into the phylogeographic distribution of the 3FTx/PLA2 venom dichotomy across genus Micrurus in South America

L Sanz, S Quesada-Bernat, T Ramos… - Journal of …, 2019 - Elsevier
Micrurus is a monophyletic genus of venomous coral snakes of the family Elapidae. The~ 80
recognized species within this genus are endemic to the Americas, and are distributed from …

Snake venom potency and yield are associated with prey‐evolution, predator metabolism and habitat structure

K Healy, C Carbone, AL Jackson - Ecology letters, 2019 - Wiley Online Library
Snake venom is well known for its ability to incapacitate and kill prey. Yet, potency and the
amount of venom available varies greatly across species, ranging from the seemingly …

The geographic mosaic of arms race coevolution is closely matched to prey population structure

MTJ Hague, AN Stokes, CR Feldman… - Evolution …, 2020 - academic.oup.com
Reciprocal adaptation is the hallmark of arms race coevolution. Local coadaptation between
natural enemies should generate a geographic mosaic pattern where both species have …