Nanocarriers mediated delivery of methotrexate is instrumental in treating auto-immune diseases and cancer

S Kumar, NK Garg, A Jain, A Khopade… - Journal of Drug Delivery …, 2023 - Elsevier
Methotrexate (MTX) is used extensively in cancer chemotherapy and for the management of
various autoimmune disorders such as rheumatoid arthritis and psoriasis. The well reported …

[HTML][HTML] Chitosan-Linseed mucilage polyelectrolyte complex nanoparticles of Methotrexate: In vitro cytotoxic efficacy and toxicological studies

SA Ghumman, A Mahmood, S Noreen, A Aslam… - Arabian Journal of …, 2023 - Elsevier
The goal of this research was to develop, fabricate and analyze polymeric nanoparticles for
the administration of methotrexate (MTX). Linseed mucilage and chitosan nanoparticles …

Cationic nanoparticles-based approaches for immune tolerance induction in vivo

K Mao, J Wang, Q Xie, YG Yang, S Shen, T Sun… - Journal of Controlled …, 2024 - Elsevier
The development of autoimmune diseases and the rejection of transplanted organs are
primarily caused by an exaggerated immune response to autoantigens or graft antigens …

Mesoporous carbon material prepared from sewage sludge hydrochar using Pluronic F127 as template for efficient removal of phenolic compounds: Experimental …

L Wang, K Lü, Y Chang, X Cao, Q Huo - Journal of Environmental …, 2023 - Elsevier
Mesoporous carbon material (MCM) with rich ether surface group was prepared from
sewage sludge hydrochar using Pluronic F127 as template under pyrolysis activation, which …

[HTML][HTML] A self-fused peptide-loaded hydrogel with injectability and tissue-adhesiveness for preventing postoperative peritoneal adhesions

Z Zhang, C Yin, X Song, X Liu, C Zhong, J Zheng… - Materials Today Bio, 2024 - Elsevier
Peritoneal adhesions commonly occur following abdominal or pelvic surgery and can cause
serious complications. Currently, physical barriers are the primary approach used in clinical …

Methotrexate-Loaded Surface-Modified Solid Lipid Nanoparticles Targeting Cancer Expressing COX-2 Enzyme

S Patra, J Dey, S Kar, A Chakraborty, M Tawate - Langmuir, 2024 - ACS Publications
Cancer is a major public health problem worldwide, and it is the second leading cause of
death of humans in the world. The present study has been directed toward the preparation of …

Cisplatin-loaded thermoresponsive liposomes for enhanced anticancer efficacy

H Shah, A Madni, N Filipczak, N Jan, MM Khan… - Journal of Drug Delivery …, 2023 - Elsevier
Thermoresponsive drug delivery systems have been used previously to deliver
chemotherapeutic agents to tumors in a hyperthermic microenvironment. The objective of …

Syringeable hydrogel based β-cyclodextrin and mixed micelles for methotrexate delivery

TT Tran, MT Nguyen, TH Luong, DT Nguyen… - Journal of Drug Delivery …, 2024 - Elsevier
Herein, mixed micelles laden hydrogel with syringeable feature were designed for intra-
articular route of Methotrexate (MTX). The ternary system (FP–B58) based on mixed Pluronic …

Fabrication of NiO nanoparticles modified with carboxymethyl cellulose and D-carvone for enhanced antimicrobial, antioxidant and anti-cancer activities

AH Falemban, IAA Ibrahim, GA Bamagous… - Inorganic Chemistry …, 2025 - Elsevier
Colon cancer is a deadly disease while pathogens such as Klebsiella pneumoniae (K.
pneumoniae), Shigella dysenteriae (S. dysenteriae), Bacillus subtilis (B. subtilis) …

Tannic Acid-Based Biomimetic Nanomedicine with Pathological Reactive Oxygen Species-Responsive Cargo Release for Relieving Inflammation in Rheumatoid …

X Zhao, S Wu, S Ni, Y Zhong, X Qin… - … Applied Materials & …, 2024 - ACS Publications
Rheumatoid arthritis (RA) is a chronic disease characterized by immune cell infiltration and
cartilage damage. The local lesion of RA shows severe oxidative stress and proinflammatory …