Getting the right combination to break the epigenetic code
Rapid advances in the field of epigenetics have facilitated the development of novel
therapeutics targeting epigenetic mechanisms that are hijacked by cancer cells to support …
therapeutics targeting epigenetic mechanisms that are hijacked by cancer cells to support …
An overview of BAP1 biological functions and current therapeutics
AM Elsayed, M Kittaneh, CM Cebulla… - … et Biophysica Acta (BBA …, 2025 - Elsevier
Abstract BRCA1-associated protein 1 (BAP1) is a tumor suppressor gene that was first
identified in 1998. Germline loss of functional variants in BAP1 is associated with a tumor …
identified in 1998. Germline loss of functional variants in BAP1 is associated with a tumor …
Targeted Therapy in Mesotheliomas: Uphill All the Way
E Bertoli, E De Carlo, M Bortolot, B Stanzione… - Cancers, 2024 - mdpi.com
Simple Summary The search for precision medicine applications in mesotheliomas (MM) is
taking its first steps. After platinum and pemetrexed chemotherapy, the treatment for …
taking its first steps. After platinum and pemetrexed chemotherapy, the treatment for …
A case of rhabdoid meningioma originating from the optic nerve
J Liu, Z Yan, F Lin, X Liu - Neuropathology, 2025 - Wiley Online Library
We report a rare case of rhabdoid meningioma (RM) originating from the optic nerve in a 57‐
year‐old female. The tumor exhibited rhabdoid or epithelioid histology and harbored BAP1 …
year‐old female. The tumor exhibited rhabdoid or epithelioid histology and harbored BAP1 …