As diseases caused by new and emerging viruses continue to be a major threat to humans
and animals worldwide the need for new therapeutic options intensifies. A wide variety of …

Effective vaccines are slowing the COVID-19 pandemic, but SARS-CoV-2 will likely remain
an issue in the future making it important to have therapeutics to treat patients. There are few …

Clopidogrel is a widely prescribed prodrug with anti-thrombotic activity through irreversible
inhibition of the P2Y12 receptor on platelets. It is FDA-approved for the clinical management …

RNA viruses like SARS-CoV-2, influenza virus, and respiratory syncytial virus (RSV) are
dependent on host genes for replication. We investigated if probenecid, an FDA-approved …

Influenza virus infection is initiated by the attachment of the viral haemagglutinin (HA)
protein to sialic acid receptors on the host cell surface. Most virus particles enter cells …

Avian influenza (AI) viruses cause infection in birds and humans. Several H5N1 and H7N9
variants are highly pathogenic avian influenza (HPAI) viruses. H5N1 is a highly infectious …

Influenza viruses cause respiratory tract infections and substantial health concerns. Infection
may result in mild to severe respiratory disease associated with morbidity and some …

Schistosomes are parasitic flatworms that cause schistosomiasis, a neglected tropical
disease of worldwide importance. Since standard treatment of schistosomiasis relies on a …

Objective To examine the precise function of influenza A virus target genes (IATGs) in
malignancy. Methods Using multi-omics data from the TCGA and TCPA datasets, 33 tumor …

SLC26A4/Pendrin is the major electroneutral Cl−/HCO3− exchanger of the apical
membrane of the Type B intercalated cell (IC) of the connecting segment (CNT) and cortical …