To faithfully segregate chromosomes during vertebrate mitosis, kinetochore–microtubule
interactions must be restricted to a single site on each chromosome. Prior work on pair-wise …

Abl family kinases are evolutionarily conserved regulators of cell migration and
morphogenesis. Genetic experiments in Drosophila suggest that Abl family kinases interact …

Cytoplasmic linker-associated proteins (CLASPs) regulate microtubules in fundamental
cellular processes. CLASPs stabilize dynamic microtubules by suppressing microtubule …

Precise design and control of molecular self‐assembly as living creatures are exciting ideas
in the field of nanotechnology. Characterized with predesigned geometries and accurate …

Post-translational cycles of α-tubulin detyrosination and tyrosination generate microtubule
diversity, the cellular functions of which remain largely unknown. Here we show that α …

GTP-tubulin is preferentially incorporated at growing microtubule ends, but the biochemical
mechanism by which the bound nucleotide regulates the strength of tubulin: tubulin …

Microtubules (MTs) are dynamic cytoskeletal polymers that play a critical role in determining
cell polarity and shape. In plant cells, acentrosomal MTs are localized on the cell surface …

Microtubules are essential cytoskeletal polymers, which exhibit stochastic transitions
between assembly and disassembly, known as catastrophes and rescues. Understanding of …

The microtubule cytoskeleton undergoes major reorganizations during mitosis, process
extension, and ciliogenesis. To achieve these rearrangements, cells must rapidly increase …