Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

A history of exploring cancer in context

S Maman, IP Witz - Nature Reviews Cancer, 2018 - nature.com
The concept that progression of cancer is regulated by interactions of cancer cells with their
microenvironment was postulated by Stephen Paget over a century ago. Contemporary …

Self‐assembled peptide‐based nanomaterials for biomedical imaging and therapy

GB Qi, YJ Gao, L Wang, H Wang - Advanced materials, 2018 - Wiley Online Library
Peptide‐based materials are one of the most important biomaterials, with diverse structures
and functionalities. Over the past few decades, a self‐assembly strategy is introduced to …

Gadolinium‐based contrast agents for magnetic resonance cancer imaging

Z Zhou, ZR Lu - Wiley Interdisciplinary Reviews: Nanomedicine …, 2013 - Wiley Online Library
Magnetic resonance imaging (MRI) is a clinical imaging modality effective for anatomical
and functional imaging of diseased soft tissues, including solid tumors. MRI contrast agents …

Targeting of drugs and nanoparticles to tumors

E Ruoslahti, SN Bhatia, MJ Sailor - Journal of cell biology, 2010 - rupress.org
The various types of cells that comprise the tumor mass all carry molecular markers that are
not expressed or are expressed at much lower levels in normal cells. These differentially …

Functionalization of inorganic nanoparticles for bioimaging applications

N Erathodiyil, JY Ying - Accounts of chemical research, 2011 - ACS Publications
Modern biomedical imaging technologies have led to significant advances in diagnosis and
therapy. Because most disease processes occur at the molecular and cellular levels …

Molecular imaging of the tumor microenvironment

Z Zhou, ZR Lu - Advanced Drug Delivery Reviews, 2017 - Elsevier
The tumor microenvironment plays a critical role in tumor initiation, progression, metastasis,
and resistance to therapy. It is different from normal tissue in the extracellular matrix …

Peptides as targeting elements and tissue penetration devices for nanoparticles

E Ruoslahti - Advanced materials, 2012 - Wiley Online Library
The use of nanoparticles in medicine (nanomedicine) has recently become an intensely
studied field. Nanoparticles carrying drugs and imaging agents have already reached the …

The use of therapeutic peptides to target and to kill cancer cells

RJ Boohaker, MW Lee, P Vishnubhotla… - Current medicinal …, 2012 - ingentaconnect.com
Peptide therapeutics is a promising field for emerging anti-cancer agents. Benefits include
the ease and rapid synthesis of peptides and capacity for modifications. An existing and vast …

Targeted contrast agents for magnetic resonance molecular imaging of cancer

ZR Lu, V Laney, Y Li - Accounts of chemical research, 2022 - ACS Publications
Conspectus Magnetic resonance imaging (MRI) is a clinical imaging modality that provides
high-resolution images of soft tissues, including cancerous lesions. Stable gadolinium (III) …