Structure–activity relationship of benzofuran derivatives with potential anticancer activity

J Farhat, L Alzyoud, M Alwahsh, B Al-Omari - Cancers, 2022 - mdpi.com
Simple Summary Cancer is the leading cause of death worldwide and responsible for killing
approximately 10 million people per year. Fused heterocyclic ring systems such as …

Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades

T Efferth, O Kadioglu, MEM Saeed, EJ Seo… - Phytochemistry …, 2021 - Springer
Multidrug resistance is a major factor causing the failure of cancer chemotherapy. Efflux
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …

Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines

LM Youmbi, YSD Makong, AT Mbaveng… - … Medicine and Therapies, 2023 - Springer
Background Cancer remains a global health concern and constitutes an important barrier to
increasing life expectancy. Malignant cells rapidly develop drug resistance leading to many …

N-acetylglycoside of oleanolic acid (aridanin) displays promising cytotoxicity towards human and animal cancer cells, inducing apoptotic, ferroptotic and necroptotic …

AT Mbaveng, GF Chi, IN Bonsou, S Abdelfatah… - Phytomedicine, 2020 - Elsevier
Background The discovery of novel phytochemicals represents a reasonable approach to
fight malignancies, especially those which are resistant to standard chemotherapy. Purpose …

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …

8, 8-bis-(Dihydroconiferyl)-diferulate displayed impressive cytotoxicity towards a panel of human and animal cancer cells

AT Mbaveng, F Damen, MGF Guefack, SB Tankeo… - Phytomedicine, 2020 - Elsevier
Background Recalcitrant cancers appear as a major obstacle to chemotherapy, prompting
scientists to intensify the search for novel drugs to tackle the cell lines expressing multi-drug …

Cytotoxic Constituents of the Bark of Hypericum roeperianum towards Multidrug‐Resistant Cancer Cells

MGF Guefack, F Damen, AT Mbaveng… - Evidence‐Based …, 2020 - Wiley Online Library
The global cancer burden remains a serious concern with the alarming incidence of one in
eight men and one in eleven women dying in developing countries. This situation is …

Potential antibacterial pharmaceuticals from the flora of Africa

AT Mbaveng, LK Omosa, GTM Bitchagno… - Advances in Botanical …, 2023 - Elsevier
The present chapter highlights the antibacterial potential of nine highly active compounds
isolated from the African medicinal plants: 8, 8-bis-(dihydroconiferyl)-diferulate, buesgenine …

[PDF][PDF] Phytochemistry and pharmacology of Imperata cylindrica: A comprehensive review

P Nayim, AT Mbaveng, K Sudhir… - Invest Med Chem …, 2023 - researchgate.net
Background: Imperata cylindrica is a medicinal spice used in traditional medicine to cure
several ailments including cancer, wounds, hypertension, and inflammation. The current …

Coumarins as potential anti-drug resistant cancer agents: A mini review

G Wang, S Sun, B Wu, J Liu - Current topics in medicinal …, 2021 - ingentaconnect.com
Cancer is the main cause of death, and the emergence of resistance by cancer cells towards
existing anticancer agents is one of the major problems for effective chemotherapy, creating …