Neospora caninum–how close are we to development of an efficacious vaccine that prevents abortion in cattle?

MP Reichel, JT Ellis - International journal for parasitology, 2009 - Elsevier
Neospora caninum is a protozoan parasite that causes abortion in cattle around the world.
Although the clinical signs of disease in both dogs and cattle have now been recognised for …

Vaccines against neosporosis: what can we learn from the past studies?

T Monney, A Hemphill - Experimental parasitology, 2014 - Elsevier
Neospora caninum is an intracellular apicomplexan parasite, which is a leading cause of
abortion in cattle; thus neosporosis represents an important veterinary health problem and is …

[图书][B] Neosporosis in animals

JP Dubey, A Hemphill, R Calero-Bernal, G Schares - 2017 - taylorfrancis.com
Key features: Written by the scientist who named this parasite and was the first to set up
proper diagnostic techniques Serves as the first ever book to provide information on the …

Immune Response of Calves Vaccinated with Brucella abortus S19 or RB51 and Revaccinated with RB51

EMS Dorneles, GK Lima, A Teixeira-Carvalho… - PloS one, 2015 - journals.plos.org
Brucella abortus S19 and RB51 strains have been successfully used to control bovine
brucellosis worldwide; however, currently, most of our understanding of the protective …

Neospora caninum in non-pregnant and pregnant mouse models: cross-talk between infection and immunity

A Aguado-Martínez, AP Basto, A Leitão… - International journal for …, 2017 - Elsevier
Neospora caninum is a cyst-forming coccidian which causes abortion in cattle, with a high
economic impact globally. Vaccination is considered to be the most cost-effective strategy to …

Approaches for the vaccination and treatment of Neospora caninum infections in mice and ruminant models

A Hemphill, A Aguado-Martinez, J Mueller - Parasitology, 2016 - cambridge.org
Neospora caninum is a leading cause of abortion in cattle, and is thus an important
veterinary health problem of high economic significance. Vaccination has been considered …

Vaccination with recombinant NcROP2 combined with recombinant NcMIC1 and NcMIC3 reduces cerebral infection and vertical transmission in mice experimentally …

K Debache, F Alaeddine, C Guionaud… - International journal for …, 2009 - Elsevier
We investigated the protective potential of recombinant his-tagged antigens recNcMIC1,
recNcMIC3 and recNcROP2, applied either as single vaccines or as vaccine combinations …

Neospora caninum SRS2 Protein: Essential Vaccination Targets and Biochemical Features for Next‐Generation Vaccine Design

A Asghari, B Kordi, B Maleki, H Majidiani… - BioMed Research …, 2022 - Wiley Online Library
Vaccination is a standout preventive measure to combat neosporosis among cattle herds.
The present in silico study was done to evaluate the physicochemical properties and potent …

[PDF][PDF] Proteins mediating the Neospora caninum-host cell interaction as targets for vaccination

A Hemphill, K Debache, T Monney, M Schorer… - Front Biosci (Elite …, 2013 - researchgate.net
Neospora caninum and neosporosis 3. Host cell adhesion/invasion by N. caninum and
related apicomplexan parasites 3.1. Initial adhesion is mediated by surface antigens (SAGs) …

[HTML][HTML] Myeloid differentiation factor 88 is required for resistance to Neospora caninum infection

TWP Mineo, L Benevides, NM Silva, JS Silva - Veterinary research, 2009 - ncbi.nlm.nih.gov
Neospora caninum is an intracellular parasite that causes major economic impact on cattle
raising farms, and infects a wide range of warm-blooded hosts worldwide. Innate immune …