Pathogenesis and Clinical Relevance of Candida Biofilms in Vulvovaginal Candidiasis

C Rodríguez-Cerdeira, E Martínez-Herrera… - Frontiers in …, 2020 - frontiersin.org
The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …

Farnesol and Tyrosol: Secondary Metabolites with a Crucial quorum-sensing Role in Candida Biofilm Development

CF Rodrigues, L Černáková - Genes, 2020 - mdpi.com
When living in biological and interactive communities, microorganisms use quorum-sensing
mechanisms for their communication. According to cell density, bacteria and fungi can …

Mixed biofilms of pathogenic Candida-bacteria: regulation mechanisms and treatment strategies

F Khan, NI Bamunuarachchi, DTN Pham… - Critical reviews in …, 2021 - Taylor & Francis
Mixed-species biofilm is one of the most frequently recorded clinical problems. Mixed
biofilms develop as a result of interactions between microorganisms of a single or multiple …

Fungal Quorum-Sensing Molecules: A Review of Their Antifungal Effect against Candida Biofilms

R Kovács, L Majoros - Journal of Fungi, 2020 - mdpi.com
The number of effective therapeutic strategies against biofilms is limited; development of
novel therapies is urgently needed to treat a variety of biofilm-associated infections. Quorum …

Effects of tyrosol and farnesol on Candida albicans biofilm

S Sebaa, Z Boucherit-Otmani… - Molecular medicine …, 2019 - spandidos-publications.com
The present in vitro study examined the effects of the quorum-sensing molecules farnesol
and tyrosol on the development of Candida albicans biofilm in order to elucidate their role as …

In vitro and in vivo Effect of Exogenous Farnesol Exposure Against Candida auris

F Nagy, E Vitális, Á Jakab, AM Borman… - Frontiers in …, 2020 - frontiersin.org
The spreading of multidrug-resistant Candida auris is considered as an emerging global
health threat. The number of effective therapeutic regimens is strongly limited; therefore …

Plausible Mechanistic Insights in Biofilm Eradication Potential against Candida spp. Using In Situ-Synthesized Tyrosol-Functionalized Chitosan Gold Nanoparticles …

TC Yadav, P Gupta, S Saini, S Mohiyuddin, V Pruthi… - ACS …, 2022 - ACS Publications
In the present study, tyrosol-functionalized chitosan gold nanoparticles (Chi-TY-AuNPs)
were prepared as an alternative treatment strategy to combat fungal infections. Various …

Harnessing yeast metabolism of aromatic amino acids for fermented beverage bioflavouring and bioproduction

AG Cordente, S Schmidt, G Beltran, MJ Torija… - Applied microbiology …, 2019 - Springer
Aromatic amino acid metabolism in yeast is an important source of secondary compounds
that influence the aroma and flavour of alcoholic beverages and foods. Examples are the …

Farnesol Boosts the Antifungal Effect of Fluconazole and Modulates Resistance in Candida auris through Regulation of the CDR1 and ERG11 Genes

J Dekkerová, L Černáková, S Kendra, E Borghi… - Journal of Fungi, 2022 - mdpi.com
Candida auris is considered a serious fungal pathogen frequently exhibiting a high
resistance to a wide range of antifungals. In this study, a combination of the quorum-sensing …

Novel Therapies for Biofilm-Based Candida spp. Infections

L Černáková, C Light, B Salehi… - … Infectious Diseases and …, 2019 - Springer
The presence of fungal infections continue to grow worldwide, mostly in immunosuppressed
patients, and in individuals with continued antimicrobial treatments. Candida spp. are the …