The golden egg: nutritional value, bioactivities, and emerging benefits for human health

S Réhault-Godbert, N Guyot, Y Nys - Nutrients, 2019 - mdpi.com
Egg is an encapsulated source of macro and micronutrients that meet all requirements to
support embryonic development until hatching. The perfect balance and diversity in its …

One-carbon metabolism in health and disease

GS Ducker, JD Rabinowitz - Cell metabolism, 2017 - cell.com
One-carbon (1C) metabolism, mediated by the folate cofactor, supports multiple
physiological processes. These include biosynthesis (purines and thymidine), amino acid …

Dietary choline intake: current state of knowledge across the life cycle

AM Wiedeman, SI Barr, TJ Green, Z Xu, SM Innis… - Nutrients, 2018 - mdpi.com
Choline, an essential dietary nutrient for humans, is required for the synthesis of the
neurotransmitter, acetylcholine, the methyl group donor, betaine, and phospholipids; and …

Dietary cholesterol and the lack of evidence in cardiovascular disease

GA Soliman - Nutrients, 2018 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death in the United States. For years,
dietary cholesterol was implicated in increasing blood cholesterol levels leading to the …

The relationship between choline bioavailability from diet, intestinal microbiota composition, and its modulation of human diseases

N Arias, S Arboleya, J Allison, A Kaliszewska… - Nutrients, 2020 - mdpi.com
Choline is a water-soluble nutrient essential for human life. Gut microbial metabolism of
choline results in the production of trimethylamine (TMA), which, upon absorption by the host …

[HTML][HTML] Choline: the underconsumed and underappreciated essential nutrient

TC Wallace, JK Blusztajn, MA Caudill, KC Klatt… - Nutrition …, 2018 - journals.lww.com
Choline has been recognized as an essential nutrient by the Food and Nutrition Board of the
National Academies of Medicine since 1998. Its metabolites have structural, metabolic, and …

SGLT2 inhibition, choline metabolites, and cardiometabolic diseases: a mediation Mendelian randomization study

M Xu, J Zheng, T Hou, H Lin, T Wang, S Wang… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE To investigate the causal role of choline metabolites mediating sodium–glucose
cotransporter 2 (SGLT2) inhibition in coronary artery disease (CAD) and type 2 diabetes …

[HTML][HTML] ESPEN micronutrient guideline

MM Berger, A Shenkin, A Schweinlin, K Amrein… - Clinical Nutrition, 2022 - Elsevier
Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. Recent research has shown the importance of MNs in …

Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation

R Velazquez, E Ferreira, S Knowles, C Fux… - Aging cell, 2019 - Wiley Online Library
Currently, there are no effective therapies to ameliorate the pathological progression of
Alzheimer's disease (AD). Evidence suggests that environmental factors may contribute to …

Lipids in human milk

H Demmelmair, B Koletzko - … Practice & Research Clinical Endocrinology & …, 2018 - Elsevier
Fat is the main energy providing component in human milk and comprising a complex
mixture of different lipid species, with quantitative dominance of triglycerides. After …