Advances in DNA sequencing and other technologies have greatly facilitated the
identification of genetic risk factors for inherited diseases in dogs. We review recent …

Non-human primates play a key role in the preclinical validation of pluripotent stem cell-
based cell replacement therapies. Pluripotent stem cells used as advanced therapy medical …

Reconstitution of germ cell fate from pluripotent stem cells provides an opportunity to
understand the molecular underpinnings of germ cell development. Here, we established …

Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical
studies because of its comparable physiology and organ size to humans. The derivation of …

Abstract In 2006, Shinya Yamanaka generated induced pluripotent stem cells (iPSCs),
which has been the major scientific event of the decade that caught the eye of many …

The giant panda (Ailuropoda melanoleuca) stands as a flagship and umbrella species,
symbolizing global biodiversity. While traditional assisted reproductive technology faces …

Genome integration‐free pig induced pluripotent stem cells (iPSCs) bring tremendous value
in pre‐clinical testing of regenerative medicine, as well as conservation and exploitation of …

Pluripotent stem cells (PSCs) harbor the capacity of unlimited self-renewal and multilineage
differentiation potential, which are crucial for basic research and biomedical science …

In the past decade, the potential to translate scientific discoveries in the area of regenerative
therapeutics in veterinary species to novel, effective human therapies has gained interest …

Heart failure (HF) is the leading cause of death worldwide. The most effective HF treatment
is heart transplantation, the use of which is restricted by the limited supply of donor hearts …