Precision drug delivery to the central nervous system using engineered nanoparticles

J Gao, Z Xia, S Gunasekar, C Jiang, JM Karp… - Nature Reviews …, 2024 - nature.com
Abstract Development of novel therapies for central nervous system (CNS) disorders has
experienced a high failure rate in clinical trials owing to unsatisfactory efficacy and adverse …

Nanoparticle toxicology

W Yang, L Wang, EM Mettenbrink… - Annual Review of …, 2021 - annualreviews.org
Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …

Antibacterial action of nanoparticles by lethal stretching of bacterial cell membranes

DP Linklater, VA Baulin, X Le Guével… - Advanced …, 2020 - Wiley Online Library
It is commonly accepted that nanoparticles (NPs) can kill bacteria; however, the mechanism
of antimicrobial action remains obscure for large NPs that cannot translocate the bacterial …

Environmental applications of graphene-based nanomaterials

F Perreault, AF De Faria, M Elimelech - Chemical Society Reviews, 2015 - pubs.rsc.org
Graphene-based materials are gaining heightened attention as novel materials for
environmental applications. The unique physicochemical properties of graphene, notably its …

[HTML][HTML] Nanoparticle-assisted ultrasound: A special focus on sonodynamic therapy against cancer

G Canavese, A Ancona, L Racca, M Canta… - Chemical Engineering …, 2018 - Elsevier
At present, ultrasound radiation is broadly employed in medicine for both diagnostic and
therapeutic purposes at various frequencies and intensities. In this review article, we focus …

Antimicrobial properties of graphene oxide nanosheets: why size matters

F Perreault, AF De Faria, S Nejati, M Elimelech - ACS nano, 2015 - ACS Publications
Graphene oxide (GO) is a promising material for the development of antimicrobial surfaces
due to its contact-based antimicrobial activity. However, the relationship between GO …

Enhanced antibacterial activity through the controlled alignment of graphene oxide nanosheets

X Lu, X Feng, JR Werber, C Chu… - Proceedings of the …, 2017 - National Acad Sciences
The cytotoxicity of 2D graphene-based nanomaterials (GBNs) is highly important for
engineered applications and environmental health. However, the isotropic orientation of …

Understanding nanoparticle cellular entry: a physicochemical perspective

CM Beddoes, CP Case, WH Briscoe - Advances in colloid and interface …, 2015 - Elsevier
Understanding interactions between nanoparticles (NPs) with biological matter, particularly
cells, is becoming increasingly important due to their growing application in medicine and …

Nanoantibiotics: Functions and properties at the nanoscale to combat antibiotic resistance

MM Mamun, AJ Sorinolu, M Munir… - Frontiers in …, 2021 - frontiersin.org
One primary mechanism for bacteria developing resistance is frequent exposure to
antibiotics. Nanoantibiotics (nAbts) is one of the strategies being explored to counteract the …

How toxic are gold nanoparticles? The state-of-the-art

I Fratoddi, I Venditti, C Cametti, MV Russo - Nano Research, 2015 - Springer
With the growing interest in the applications of gold nanoparticles in biotechnology and their
physiological effects, possible toxicity of gold nanoparticles is becoming an increasingly …