Bacterial insertion sequences: their genomic impact and diversity
P Siguier, E Gourbeyre… - FEMS microbiology …, 2014 - academic.oup.com
Insertion sequences (ISs), arguably the smallest and most numerous autonomous
transposable elements (TEs), are important players in shaping their host genomes. This …
transposable elements (TEs), are important players in shaping their host genomes. This …
Nucleases: diversity of structure, function and mechanism
W Yang - Quarterly reviews of biophysics, 2011 - cambridge.org
Nucleases cleave the phosphodiester bonds of nucleic acids and may be endo or exo,
DNase or RNase, topoisomerases, recombinases, ribozymes, or RNA splicing enzymes. In …
DNase or RNase, topoisomerases, recombinases, ribozymes, or RNA splicing enzymes. In …
Structural mechanism of bridge RNA-guided recombination
M Hiraizumi, NT Perry, MG Durrant, T Soma… - Nature, 2024 - nature.com
Insertion sequence (IS) elements are the simplest autonomous transposable elements found
in prokaryotic genomes. We recently discovered that IS110 family elements encode a …
in prokaryotic genomes. We recently discovered that IS110 family elements encode a …
[HTML][HTML] Crystal structure of Cas9 in complex with guide RNA and target DNA
The CRISPR-associated endonuclease Cas9 can be targeted to specific genomic loci by
single guide RNAs (sgRNAs). Here, we report the crystal structure of Streptococcus …
single guide RNAs (sgRNAs). Here, we report the crystal structure of Streptococcus …
Argonaute2 is the catalytic engine of mammalian RNAi
J Liu, MA Carmell, FV Rivas, CG Marsden… - Science, 2004 - science.org
Gene silencing through RNA interference (RNAi) is carried out by RISC, the RNA-induced
silencing complex. RISC contains two signature components, small interfering RNAs …
silencing complex. RISC contains two signature components, small interfering RNAs …
Crystal structure of Argonaute and its implications for RISC slicer activity
JJ Song, SK Smith, GJ Hannon, L Joshua-Tor - science, 2004 - science.org
Argonaute proteins and small interfering RNAs (siRNAs) are the known signature
components of the RNA interference effector complex RNA-induced silencing complex …
components of the RNA interference effector complex RNA-induced silencing complex …
Recent advances in zinc enzymology
WN Lipscomb, N Sträter - Chemical Reviews, 1996 - ACS Publications
Posters and lectures presented at the Seventh International Conference on Bioinorganic
Chemistry (ICBIC) in Lubeck, Germany, last year was divided into 16 sections, including …
Chemistry (ICBIC) in Lubeck, Germany, last year was divided into 16 sections, including …
Recombinational Repair of DNA Damage inEscherichia coli and Bacteriophage λ
A Kuzminov - Microbiology and molecular biology reviews, 1999 - Am Soc Microbiol
Although homologous recombination and DNA repair phenomena in bacteria were initially
extensively studied without regard to any relationship between the two, it is now appreciated …
extensively studied without regard to any relationship between the two, it is now appreciated …
Holliday junction resolvases
Four-way DNA intermediates, called Holliday junctions (HJs), can form during meiotic and
mitotic recombination, and their removal is crucial for chromosome segregation. A group of …
mitotic recombination, and their removal is crucial for chromosome segregation. A group of …
[HTML][HTML] Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis
M Nowotny, SA Gaidamakov, RJ Crouch, W Yang - Cell, 2005 - cell.com
RNase H belongs to a nucleotidyl-transferase superfamily, which includes transposase,
retroviral integrase, Holliday junction resolvase, and RISC nuclease Argonaute. We report …
retroviral integrase, Holliday junction resolvase, and RISC nuclease Argonaute. We report …