Ambulatory reflux monitoring for diagnosis of gastro‐esophageal reflux disease: update of the Porto consensus and recommendations from an international …

S Roman, CP Gyawali, E Savarino… - …, 2017 - Wiley Online Library
Background An international group of experts evaluated and revised recommendations for
ambulatory reflux monitoring for the diagnosis of gastro‐esophageal reflux disease (GERD) …

The appropriate use of proton pump inhibitors (PPIs): need for a reappraisal

V Savarino, P Dulbecco, N de Bortoli… - European journal of …, 2017 - Elsevier
The advent of powerful acid-suppressive drugs, such as proton pump inhibitors (PPIs), has
revolutionized the management of acid-related diseases and has minimized the role of …

Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and …

R Rosen, Y Vandenplas, M Singendonk… - Journal of pediatric …, 2018 - journals.lww.com
This document serves as an update of the North American Society for Pediatric
Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for …

Analyses of the post-reflux swallow-induced peristaltic wave index and nocturnal baseline impedance parameters increase the diagnostic yield of impedance-pH …

M Frazzoni, E Savarino, N de Bortoli, I Martinucci… - Clinical …, 2016 - Elsevier
Background & Aims Analyses of impedance parameters such as the post-reflux swallow-
induced peristaltic wave (PSPW) index and the mean nocturnal baseline impedance (MNBI) …

[HTML][HTML] Advances in the physiological assessment and diagnosis of GERD

E Savarino, AJ Bredenoord, M Fox… - Nature reviews …, 2017 - nature.com
GERD is a common condition worldwide. Key mechanisms of disease include abnormal
oesophagogastric junction structure and function, and impaired oesophageal clearance. A …

Classification of esophageal motor findings in gastro‐esophageal reflux disease: conclusions from an international consensus group

CP Gyawali, S Roman, AJ Bredenoord… - …, 2017 - Wiley Online Library
Background High‐resolution manometry (HRM) has resulted in new revelations regarding
the pathophysiology of gastro‐esophageal reflux disease (GERD). The impact of new HRM …

EAES recommendations for the management of gastroesophageal reflux disease

KH Fuchs, B Babic, W Breithaupt, B Dallemagne… - Surgical …, 2014 - Springer
Background Gastroesophageal reflux disease (GERD) is one of the most frequent benign
disorders of the upper gastrointestinal tract. Management of GERD has always been …

[HTML][HTML] Gastroesophageal reflux disease, functional dyspepsia and irritable bowel syndrome: common overlapping gastrointestinal disorders

N De Bortoli, S Tolone, M Frazzoni… - Annals of …, 2018 - ncbi.nlm.nih.gov
Several studies have indicated an overlap between gastroesophageal reflux disease
(GERD) and various functional gastrointestinal disorders (FGIDs). The overlapping …

Esophageal baseline impedance levels in patients with pathophysiological characteristics of functional heartburn

I Martinucci, N de Bortoli, E Savarino… - …, 2014 - Wiley Online Library
Background Recently, it has been suggested that low esophageal basal impedance may
reflect impaired mucosal integrity and increased acid sensitivity. We aimed to compare …

NERD: an umbrella term including heterogeneous subpopulations

E Savarino, P Zentilin, V Savarino - Nature reviews Gastroenterology & …, 2013 - nature.com
Nonerosive reflux disease (NERD) represents the more common phenotypic presentation of
GERD and comprises patients who have typical symptoms without any mucosal breaks at …