Our body handles tissue damage by activating the immune system in response to
intracellular molecules released by injured tissues [damage-associated molecular patterns …

Adult mesenchymal stem cells (MSCs) represent a subject of intense experimental and
biomedical interest. Recently, trophic activities of MSCs have become the topic of a number …

Purpose: We hypothesized that autophagy inhibition would increase response to
chemotherapy in the preoperative setting for patients with pancreatic adenocarcinoma. We …

Thrombosis and inflammation are intricately linked in several major clinical disorders,
including disseminated intravascular coagulation and acute ischemic events. The damage …

This is the first study to investigate the hepatoprotective effect of CQ on acute liver injury
caused by carbon tetrachloride (CCl4) in a murine model and the underlying molecular …

The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy
can function as in situ cancer vaccination by exposing tumor antigens and providing …

Autoimmune response to cardiac troponin I (TnI) induces inflammation and fibrosis in the
myocardium. High-mobility group box 1 (HMGB1) is a multifunctional protein that exerts …

The treatment of sepsis and septic shock remains a major public health issue due to the
associated morbidity and mortality. Despite an improvement in the understanding of the …

A key inflammatory mechanism recently identified in platelets involves the Nod-like receptor
nucleotide-binding domain leucine-rich repeat containing protein 3 (NLRP3) and Bruton …

Mesenchymal stem cells (MSCs) are widely distributed pluripotent stem cells with powerful
immunomodulatory capacity. MSCs transplantation therapy (MSCT) is widely used in the …