In patients with end-stage renal disease (ESRD) treated with haemodialysis or peritoneal
dialysis, hypertension is common and often poorly controlled. Blood pressure (BP) …

Cardiovascular disease (CVD) is prevalent worldwide and remains a leading cause of
death. Although substantial progress has been made in the diagnosis and treatment of CVD …

Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …

The kidney plays a fundamental role in maintaining body salt and fluid balance and blood
pressure homeostasis through the actions of its proximal and distal tubular segments of …

Renalase is a novel flavoprotein, highly expressed in kidney and heart, which metabolizes
catecholamines and catecholamine-like substances via a superoxide (O2–)-dependent …

Abstract Hypertension (blood pressure> 140/90 mm Hg) is very common in patients
undergoing regular dialysis, with a prevalence of 70-80%, and only the minority has …

An inverse relationship between body mass index (BMI) and mortality (the obesity paradox)
has been found in patients with non-dialysis-dependent chronic kidney disease (CKD) …

Despite the existence of established, effective therapies for hypertension, new methods of
blood pressure and cardiovascular risk reduction are still needed. Novel approaches are …

Elevated levels of plasma catecholamines accompany ischemic AKI, possibly contributing
the inflammatory response. Renalase, an amine oxidase secreted by the proximal tubule …

Renalase, a recently discovered flavoprotein, which is strongly expressed in the kidney and
heart, effectively metabolizes catecholamines. It was discovered during the search to identify …