Designing nanotheranostics with machine learning

L Rao, Y Yuan, X Shen, G Yu, X Chen - Nature Nanotechnology, 2024 - nature.com
The inherent limits of traditional diagnoses and therapies have driven the development and
application of emerging nanotechnologies for more effective and safer management of …

Di (2-picolyl) amine appended luminescent probes: Advances in bioimaging and therapeutics

B Das, P Gupta - Coordination Chemistry Reviews, 2025 - Elsevier
Abstract Di (2-picolyl) amine appended luminescent probes have been developed as
versatile tools for bioimaging and therapeutic applications. These probes offer real-time …

Direct mapping of tyrosine sulfation states in native peptides by nanopore

H Niu, MY Li, Y Gao, JG Li, J Jiang, YL Ying… - Nature Chemical …, 2024 - nature.com
Sulfation is considered the most prevalent post-translational modification (PTM) on tyrosine;
however, its importance is frequently undervalued due to difficulties in direct and …

Label-Free Mode Based on Ferrocene/PEDOT: PSS–PPy for Molecularly Imprinted Electrochemically Ultrasensitive Detection of Amino Acids

Z Wang, Z Chen, Z Ma, H Han - Analytical chemistry, 2024 - ACS Publications
Generally, molecularly imprinted (MIP) electrochemical sensors for amino acids operate in a
“label-like” mode. That is, after an amino acid is specifically recognized by an imprinted …

Single-molecule protein sequencing with nanopores

J Ritmejeris, X Chen, C Dekker - Nature Reviews Bioengineering, 2024 - nature.com
Protein sequencing and the identification of post-translational modifications are key to
understanding cellular signalling pathways and metabolic processes in health and disease …

Single-Molecule Identification and Quantification of Steviol Glycosides with a Deep Learning-Powered Nanopore Sensor

M Li, J Wang, C Zhang, X Zhao, Y Xiong, Y Cao… - ACS …, 2024 - ACS Publications
Steviol glycosides (SGs) are a class of high-potency noncalorie natural sweeteners made up
of a common diterpenoid core and varying glycans. Thus, the diversity of glycans in …

Simultaneous Identification of Vitamins B1, B3, B5, and B6 by an Engineered Nanopore

Y Ouyang, K Wang, W Jia, P Zhang, S Huang - Nano Letters, 2024 - ACS Publications
Vitamin Bs, a group of water-soluble compounds, are essential nutrients for almost all living
organisms. However, due to their structural heterogeneity, rapid and simultaneous analysis …

Nanopore approaches for single-molecule temporal omics: promises and challenges

MY Li, J Jiang, JG Li, H Niu, YL Ying, R Tian, YT Long - Nature Methods, 2024 - nature.com
The great molecular heterogeneity within single cells demands omics analysis from a single-
molecule perspective. Moreover, considering the perpetual metabolism and communication …

Protein nanopore-based sensors for public health analyte detection

Y Zhang, C Hu, R Liu, S He, J Yang, W Yao… - Journal of Materials …, 2024 - pubs.rsc.org
High-throughput and label-free protein nanopore-based sensors are extensively used in
DNA sequencing, single-protein analysis, molecular sensing and chemical catalysis with …

[HTML][HTML] Nanopore sensing and beyond: Electrochemical systems for optically-coupled single-entity studies, stimulus-responsive gating applications, and point-of-care …

J Reitemeier, J Metro, KX Fu - Sensors and Actuators Reports, 2024 - Elsevier
Nanopores play essential roles in biological processes, such as ion channels and pumps in
cellular membranes, and in technological applications such as DNA sequencing …