Effect of Statins on Serum level of hs‐CRP and CRP in Patients with Cardiovascular Diseases: A Systematic Review and Meta‐Analysis of Randomized Controlled …

T Kandelouei, M Abbasifard, D Imani… - Mediators of …, 2022 - Wiley Online Library
Background. Several studies have reported that statins have anti‐inflammatory effects.
Nevertheless, results of clinical trials concerning the effect of statins on the levels of C …

Antioxidant effects of statins by modulating Nrf2 and Nrf2/HO-1 signaling in different diseases

A Mansouri, Ž Reiner, M Ruscica… - Journal of Clinical …, 2022 - mdpi.com
Statins are competitive inhibitors of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and
have been used to treat elevated low-density lipoprotein cholesterol (LDL-C) for almost four …

[HTML][HTML] PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on diagnosis and therapy of lipid disorders in Poland 2021

M Banach, P Burchardt, K Chlebus… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

Improved COVID‐19 outcomes following statin therapy: an updated systematic review and meta‐analysis

A Vahedian-Azimi, SM Mohammadi… - BioMed research …, 2021 - Wiley Online Library
Background. Although vaccine rollout for COVID‐19 has been effective in some countries,
there is still an urgent need to reduce disease transmission and severity. We recently carried …

The cardioprotective actions of statins in targeting mitochondrial dysfunction associated with myocardial ischaemia-reperfusion injury

AR Bland, FM Payne, JC Ashton… - Pharmacological …, 2022 - Elsevier
During cardiac reperfusion after myocardial infarction, the heart is subjected to cascading
cycles of ischaemia reperfusion injury (IRI). Patients presenting with this injury succumb to …

Protective effects of statins on COVID-19 risk, severity and fatal outcome: a nationwide Swedish cohort study

A Santosa, S Franzén, J Nåtman, B Wettermark… - Scientific Reports, 2022 - nature.com
The impact of statins on COVID-19 remains unclear. This study aims to investigate whether
statin exposure assessed both in the population and in well-defined cohorts of COVID-19 …

Statins block mammalian target of rapamycin pathway: A possible novel therapeutic strategy for inflammatory, malignant and neurodegenerative diseases

NA Lashgari, NM Roudsari, SST Zadeh, S Momtaz… - …, 2023 - Springer
Inflammation plays a critical role in several diseases such as cancer, gastric, heart and
nervous system diseases. Data suggest that the activation of mammalian target of rapamycin …

Statin use in COVID-19 hospitalized patients and outcomes: a retrospective study

H Kouhpeikar, H Khosaravizade Tabasi… - Frontiers in …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) might affect everyone, but people with
comorbidities such as hypertension and cardiovascular disease (CVD) may often have more …

Distinct features of vascular diseases in COVID-19

A Ceasovschih, V Sorodoc, A Shor… - Journal of …, 2023 - Taylor & Francis
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic was declared in early 2020
after several unexplained pneumonia cases were first reported in Wuhan, China, and …

Effectiveness of rosuvastatin plus colchicine, emtricitabine/tenofovir and combinations thereof in hospitalized patients with COVID-19: a pragmatic, open-label …

HG Gaitán-Duarte, C Álvarez-Moreno… - …, 2022 - thelancet.com
Background The use of rosuvastatin plus colchicine and emtricitabine/tenofovir in
hospitalized patients with SARS-CoV-2 disease (COVID-19) has not been assessed. The …