Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

Inflammation promotes the development of heart failure (HF). The inflammasome is a
multimeric protein complex that plays an essential role in the innate immune response by …

Abstract Visfatin/extracellular-nicotinamide-phosphoribosyltranferase-(eNampt) is a
multifaceted adipokine enhanced in type-2-diabetes and obesity. Visfatin/eNampt cause in …

Exploring the molecular mechanisms that prevent inflammation during caloric restriction may
yield promising therapeutic targets. During fasting, activation of the nuclear receptor …

Nutrient transition metals are required cofactors for many proteins to perform functions
necessary for life. As such, the concentration of nutrient metals is carefully maintained to …

Background Recent clinical and basic research implicated a strong correlation between
NAFLD/NASH phenotypes with ectopic manifestations including neuroinflammation and …

Objective: Taohong Siwu decoction (THSWD) is one of the classic prescriptions for
promoting blood circulation and removing blood stasis, and it has a good therapeutic effect …

慢性心力衰竭(chronicheartfailure, CHF) 是各类心血管疾病的终末期阶段. CHF
的治疗方案近年虽不断完善, 但仍有较高的死亡率与住院率, 给患者及家庭带来了巨大的医疗 …

Background Neuroinflammation is a vital pathophysiological process during ischemic stroke.
Activated astrocytes play a major role in inflammation. Lipocalin-2 (LCN2), secreted by …

Adipose tissue dysfunction is a predictor for cardiovascular (CV) events and heart failure
(HF) in patient population with obesity, metabolic syndrome, and known type 2 diabetes …