Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17

T Iram, F Kern, A Kaur, S Myneni, AR Morningstar… - Nature, 2022 - nature.com
Recent understanding of how the systemic environment shapes the brain throughout life has
led to numerous intervention strategies to slow brain ageing,–. Cerebrospinal fluid (CSF) …

Matricellular proteins of the Cyr61/CTGF/NOV (CCN) family and the nervous system

AR Malik, E Liszewska, J Jaworski - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Matricellular proteins are secreted proteins that exist at the border of cells and the
extracellular matrix (ECM). However, instead of playing a role in structural integrity of the …

Long-term mild, rather than intense, exercise enhances adult hippocampal neurogenesis and greatly changes the transcriptomic profile of the hippocampus

K Inoue, M Okamoto, J Shibato, MC Lee, T Matsui… - PloS one, 2015 - journals.plos.org
Our six-week treadmill running training (forced exercise) model has revealed that mild
exercise (ME) with an intensity below the lactate threshold (LT) is sufficient to enhance …

RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation

K Nakayama, R Ohashi, Y Shinoda, M Yamazaki… - Elife, 2017 - elifesciences.org
Local regulation of synaptic efficacy is thought to be important for proper networking of
neurons and memory formation. Dysregulation of global translation influences long-term …

Rescue of metabolic alterations in AR113Q skeletal muscle by peripheral androgen receptor gene silencing

E Giorgetti, Z Yu, JP Chua, R Shimamura, L Zhao… - Cell reports, 2016 - cell.com
Spinal and bulbar muscular atrophy (SBMA), a progressive degenerative disorder, is caused
by a CAG/glutamine expansion in the androgen receptor (polyQ AR). Recent studies …

Previous early-life stress modifies acute corticosterone-induced synaptic plasticity in the medial prefrontal cortex of adolescent rats

I Majcher-Maślanka, A Solarz, K Wędzony, A Chocyk - Neuroscience, 2018 - Elsevier
Stress can either strengthen coping strategies or enhance the risk of depression and
anxiety. Synaptic plasticity is one of the key brain functions that can be affected by stress. We …

Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ErbB receptors in breast cancer cells

M Mina, S Magi, G Jurman, M Itoh, H Kawaji… - Scientific reports, 2015 - nature.com
The analysis of CAGE (Cap Analysis of Gene Expression) time-course has been proposed
by the FANTOM5 Consortium to extend the understanding of the sequence of events …

Effects of GABA a receptor antagonists on motor behavior in pharmacological Parkinson's disease model in mice

KDM Mograbi, ACF de Castro… - Physiological …, 2017 - Wiley Online Library
The aim of this study was to evaluate the effects of two gamma‐amino butyric acid (GABA) a
receptor antagonists on motor behavioral tasks in a pharmacological model of Parkinson …

Role of RGS2 in sevoflurane-induced cognitive dysfunction in aged rats.

C Hao, X Duan, X Yang, Z Huang… - Pakistan Journal of …, 2022 - search.ebscohost.com
After undergoing inhalation anesthesia, some patients, especially elderly patients,
experience postoperative cognitive dysfunction, such as personality changes and memory …

[PDF][PDF] Effects of docosahexaenoic acid or arachidonic acid supplementation on gene expression and contractile force of rat cardiomyocytes in primary culture

M Yano, Y Umehara, T Kudo, T Nakamura… - Biocell, 2021 - cdn.techscience.cn
While fatty acids play essential roles in the physiology of the myocardium, conventional
culture media contain little lipid. We previously revealed that rat neonatal myocardium …