The cancer-immunity cycle provides a framework to understand the series of events that
generate anti-cancer immune responses. It emphasizes the iterative nature of the response …

Myeloid immune cells (MICs) are potent innate immune cells serving as first responders to
invading pathogens and internal changes to cellular homeostasis. Cancer is a stage of …

Effective cancer immunotherapy is usually blocked by immunosuppressive factors in the
tumour microenvironment, resulting in tumour promotion, metastasis and recurrence. Here …

The cellular stress and immunity cycle is a cornerstone of organismal homeostasis. Stress
activates intracellular and intercellular communications within a tissue or organ to initiate …

Recent advancements in single-cell RNA sequencing (scRNA-seq) have enabled the
identification of phenotypic diversity within breast tumor tissues. However, the contribution of …

The stimulator of interferon genes (STING) pathway links innate and adaptive antitumor
immunity and therefore plays an important role in cancer immune surveillance. This has …

Abstract The Mononuclear Phagocyte System includes monocytes, macrophages, some
dendritic cells and multinuclear giant cells. These cell populations display marked …