The application of supraphysiological temperatures (> 40 C) to biological tissues causes
changes at the molecular, cellular, and structural level, with corresponding changes in tissue …

Radiofrequency ablation is an interventional technique that in recent years has come to be
employed in very different medical fields, such as the elimination of cardiac arrhythmias or …

Objectives: This study sought to examine the biophysical properties of high-power and short-
duration (HP-SD) radiofrequency ablation for pulmonary vein isolation. Background …

BACKGROUND: Open surgery effectively treats mesial temporal lobe epilepsy, but carries
the risk of neurocognitive deficits, which may be reduced with minimally invasive …

Radio-frequency (RF) hepatic ablation, offers an alternative method for the treatment of
hepatic malignancies. We employed finite-element method (FEM) analysis to determine …

A system for detecting electrode-tissue contact comprises a catheter having a location
sensor and a distal tip electrode. The catheter preferably further comprises a reference …

Advances in laser, microwave, radio-frequency, and similar technologies have given rise to
many new treatments of disease and injury that seek to raise the temperature of cells and …

(56) References Cited(57) ABSTRACT US PATENT DOCUMENTS A System for detecting
electrode-tissue contact comprises a 3,871,359 A 3/1975 Pacela........................ 324/692 multi …

Background Temperature is a frequently used parameter to describe the predicted size of
lesions computed by computational models. In many cases, however, temperature …

Electrical stimulation via implanted microelectrodes permits excitation of small, highly
localized populations of neurons, and allows access to features of neuronal organization …