Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Purpose Pituitary adenomas give rise to physical and psychological symptoms, which may
persist after biochemical cure. Growing attention has been paid to quality of life (QoL) in …

Background Quality of life (QoL) in patients with acromegaly is reduced irrespective of
disease state. The contributions of multifactorial determinants of QoL in several disease …

Abstract Introduction: Patient-reported outcomes (PROs) are of increasing importance in
clinical medicine. However, their evaluation by classic psychometric methods carries …

Objective: To determine the effect of transsphenoidal surgery on quality of life and sleep in
patients with pituitary adenomas depending on tumor type and compression of the optic …

Context: There is a close association between levels of TSH binding inhibitory
immunoglobulins (TBIIs) and Graves' ophthalmopathy (GO). In addition to the TSH receptor …

The clinical syndrome of GH deficiency (GHD) is characterized by non-specific features
including variable presence of decreased mood and general well-being, reduced bone …

Context: GH deficiency (GHD) may occur in adults with cured acromegaly (acroGHD).
Objective: Our objective was to examine the effectiveness and safety of GH replacement in …

Growth hormone deficiency (GHD) in adults is characterized by reduced quality of life and
physical fitness, skeletal fragility, increased weight and cardiovascular risk. It may be found …

Between 2% and 60% of patients with cured acromegaly may eventually develop growth
hormone deficiency. In adults, growth hormone deficiency is associated with abnormal body …