Cancer is one of the major public health issues in the world. It has become the second
leading cause of death, with approximately 75% of cancer deaths transpiring in low-or …

Apoptosis, the most extensively studied form of programmed cell death, is essential for
organismal homeostasis. Apoptotic cell death has widely been reported as a tumor …

Lead can lead to neurotoxicity and cognitive impairment. In this study, for the first time, the
protective effects and working mechanisms of apple phenolic extracts (APEs) against lead …

Colon cancer is an aggressive malignancy with very limited therapeutic approaches. The
available therapeutic agents for colon cancer show strong adverse effects and poor …

Piperlongumine (PL), a herbal drug extracted from long pepper (Piper longum L), is known
for its anti-inflammatory and anti-cancer properties. Although, its anti-cancer potential has …

In the current study, a new series of benzenesulfonamides 6a-r was designed and
synthesized as dual VEGFR-2 and FGFR1 kinase inhibitors with anti-cancer activity. The 4 …

Abstract Vascular Endothelial Growth Factor II (VEGFR-2) has been proved as a rational
target in cancer therapy. Although currently prescribed VEGFR-2 inhibitors are showing …

Abstract Extracellular Vesicles (EVs) were isolated from human umbilical cord mesenchymal
stem cells (hUCMSCs) and were further encapsulated with cannabidiol (CBD) through …

This study aimed to obtain and characterize extracted hemp oil enriched in cannabidiol
(CBD) by decarboxylation of cannabidiolic acid (CBDA) and to give new insights into its …

Aim Lead acetate impairs testicular function by enhancing testicular oxidative stress and
apoptosis. Cyperus esculentus possesses antioxidants and has shown great improvement …