G protein-coupled receptors (GPCRs) are amongst the most pharmaceutically relevant and
well-studied protein targets, yet unanswered questions in the field leave significant gaps in …

Background: The global incidence of type 2 diabetes mellitus (T2DM) has enthused the
development of new antidiabetic targets with low toxicity and long-term stability. In this …

G protein-coupled receptors (GPCR) are responsible for modulating various physiological
functions and are thus related to the pathophysiology of different diseases. Being potential …

Vegetables, fruits, and spices have a pivotal role in maintaining the metabolism and have
diversified health welfares. The food products have medicinal values (Medifood) and …

Introduction The number of diabetic patients is increasing, posing a heavy social and
economic burden worldwide. Traditional drug development technology is time-consuming …

Recent studies have identified G protein‐coupled receptor 40 (GPR40) as a promising target
for treating type 2 diabetes mellitus, and GPR40 agonists have several superior effects over …

Abstract Carbonic anhydrase-II (CA-II) catalyzes reversible hydration of carbon dioxide
leading to the formation of bicarbonate and a proton. CA-II inhibitors act as biomarkers and …

Diabetes is a foremost health problem globally susceptible to increased mortality and
morbidity. The present therapies in the antidiabetic class have sound adverse effects and …

The orphan class A G-protein coupled receptor 3 (GPR3) is highly expressed in brain and
linked with various neuronal functions, and therefore, expected to play a vital role in the …

The Galaninergic system consist of Galanin and its receptors, involved in neuromodulation
and neurotransmission. Galanin regulate its physiologic and pathologic functions by …