The hemochromatosis gene HFE was discovered in 1996, more than a century after clinical
and pathologic manifestations of hemochromatosis were reported. Linked to the major …

Hereditary hemochromatosis (HH) is a common autosomal recessive disorder causing
inappropriate dietary iron absorption that affects North Europeans. HH is associated with the …

A hemocromatose hereditária (HH) está relacionada a diversos distúrbios do metabolismo
do ferro que ocasionam sua sobrecarga tecidual. A HH clássica está associada às …

The hypothesis of the role of iron overload associated with HFE gene mutations in the
pathogenesis of nonalcoholic steatohepatitis (NASH) has been raised in recent years. In the …

Hereditary hemochromatosis is a disorder of iron metabolism characterized by increased
iron intake and progressive storage and is related to mutations in the HFE gene. Interactions …

Forty-eight adult patients with celiac disease between 15 and 68 years of age (mean, 41
years) were studied. Sixty-seven percent were female and 33% were male patients. Most of …

The hemochromatosis gene, HFE, is located on chromosome 6 in close proximity to the HLA-
A locus. Most Caucasian patients with hereditary hemochromatosis (HH) are homozygous …

Hemocromatose é uma das doenças genéticas mais freqüentes no ser humano e uma das
causas mais importantes de sobrecarga de ferro. Os objetivos deste estudo foram …

Mutations of the HFE and TFR2 genes have been associated with iron overload. HFE and
TFR2 mutations were assessed in blood donors, and the relationship with iron status was …

A hemocromatose hereditária (HH) é a mais comum doença autossômica em caucasianos e
caracteriza-se pelo aumento da absorção intestinal de ferro, o qual resulta em acúmulo …