New NSAID conjugates as potent and selective COX-2 inhibitors: synthesis, molecular modeling and biological investigation

RM Bokhtia, SS Panda, AS Girgis, N Samir, MF Said… - Molecules, 2023 - mdpi.com
New sets of ibuprofen and indomethacin conjugates comprising triazolyl heterocycle were
synthesized via click chemistry, adopting an optimized protocol through the molecular …

[HTML][HTML] Detailed metabolite profiling and in vitro studies of Urospermum picroides as a potential functional food

FR Saber, AH Elosaily, EA Mahrous, Ł Pecio, S Pecio… - Food chemistry, 2023 - Elsevier
Wild edible plants (WEP) are part of the Mediterranean culinary culture and can be used as
famine foods in times of severe food shortages. Urospermum picroides is a WEP that grows …

[HTML][HTML] Urolithin A conjugation with NSAIDs inhibits its glucuronidation and maintains improvement of Caco-2 monolayers' barrier function

M Korczak, P Roszkowski, W Skowrońska… - Biomedicine & …, 2023 - Elsevier
Urolithin A (UA) is an ellagitannin-derived postbiotic metabolite which emerged as a
promising health-boosting agent, promoting mitophagy, improving skeletal muscle function …

Metabolomic screening and urolithins metabotypes identification in the urinary metabolome of Costa Rican volunteers after blackberry (Rubus adenotrichos)-based …

JM Fallas-Ramirez, E Baltodano-Viales… - Journal of Berry …, 2024 - journals.sagepub.com
BACKGROUND: Besides providing nutritional value, functional foods have potential
beneficial effects on health. Consumers worldwide seek food products with added value …

Design, Synthesis, and Anti‐infective Effect Against Candida albicans of A New Urolithin Derivative

C Zhu, L Tang, F Zhou, Y Tang, Q Hu, C Wang… - Chemistry & … - Wiley Online Library
Deep mucosal and organ infections caused by the infestation of Candida albicans (C.
albicans) in immunocompromised patients represent a significant cause of mortality in …