BRCA1-deficient cells have increased IRE1 RNase, which degrades multiple microRNAs.
Reconstituting expression of one of these, miR-4638–5p, resulted in synthetic lethality in …

Most Nelumbo nucifera (lotus) flower buds were aborted during the growing season, notably
in low-light environments. How lotus produces so many aborted flower buds is largely …

TatD enzymes are evolutionarily conserved deoxyribonucleases associated with DNA
repair, apoptosis, development, and parasite virulence. Three TatD paralogs exist in …

Background Preterm premature rupture of membranes (PPROM) is responsible for one third
of all preterm births (PTBs). We have recently demonstrated that long noncoding RNAs …

Phloem vasculature is the route that most plant viruses use to spread widely around the
plant. In addition, phloem sap transports signals that trigger systemic defense responses to …

TatD DNase, a key enzyme in vertebrates and invertebrates, plays a pivotal role in various
physiological processes. Dugesia japonica (D. japonica), a flatworm species, has …

Identifying disease genes from human genome is a critical task in biomedical research.
Important biological features to distinguish the disease genes from the non-disease genes …

Cancers that are arising from germline mutations of the breast cancer associated gene 1
(BRCA1), which is a crucial player of homologous recombination (HR) DNA repair, are …

Mitochondria are fabulous and enigmatic structures in cells. Despite a long evolutionary
history mitochondria were originally thought the powerhouse of cells. Importantly, recent …